Type 2 diabetes is characterized by islet dysfunction resulting in hyperglycemia, which can then lead to further deterioration in islet function. A possible mechanism for hyperglycemia-induced islet dysfunction is the accumulation of advanced glycation end products (AGE). The DBA/2 mouse develops pancreatic islet dysfunction when exposed to a high glucose environment and/or obesity-induced insu...

This paper reviewed the effects of in ovo feeding application on incubation performance and chick quality broilers. Effectiveness commercial chicken broiler production have a decisive role cost as well efficiency are prerequisite for sustainable production. To date, several studies been done to improve quality, significant gains achieved this area last fifty years. The average hatchability surv...

In three experiments the following results were obtained: (a) Activity was greater both prior to and following exposure to shock among C57BL/6J mice than in DBA/2J mice, which in turn was greater than that of A/J mice. (b) Scopolamine hydrobromide increased general activity in DBA/2 and A mice, but had either no effect or decreased activity in the C57BL/6 strain. Following exposure to shock, ho...

This study recommends a probabilistic scenario approach for population projections. The benefits are better information, ease of adoption, and expert opinion on the mean and range of uncertainty. The study answers whether it matters if high and low variants cover 85% or 95% of the range. An assumption of piece-wise linear random paths may underestimate the variance of the resulting populatio...

Suppose that in the four tests Alice’s scores are 90, 95, 85, 90, and Bob’s scores are 85, 95, 90, 90. How to evaluate their scores? In this paper, we introduce the concept of ordered probability mass function which can be used to find a probability mass function with smaller variance. More interestingly, we can use it to distinguish sequences of positive numbers statistically.

cardiovascular adverse effects are interesting aspects of occupational noise exposure. one possible mechanism of these effects is an alternation in hypothalamic-pituitary-adrenal axis. our aim was to measure salivary cortisol response to relatively high-intensity noise exposure in a controlled randomized trial study. we exposed 50 male volunteers to 90 dba noise for 20 minutes and compared thei...

The erythroid defect in Diamond Blackfan anemia (DBA) is known to be intrinsic to the stem cell, but its molecular pathophysiology remains obscure. Using a 2-phase liquid erythroid culture system, we have demonstrated a consistent defect in DBA, regardless of clinical severity, including 3 first-degree relatives with normal hemoglobin levels but increased erythrocyte adenosine deaminase activit...

The erythroid defect in Diamond Blackfan anemia (DBA) is known to be intrinsic to the stem cell, but its molecular pathophysiology remains obscure. Using a 2-phase liquid erythroid culture system, we have demonstrated a consistent defect in DBA, regardless of clinical severity, including 3 first-degree relatives with normal hemoglobin levels but increased erythrocyte adenosine deaminase activit...

Epilepsy Interleukin-2 Convulsants Audiogenic seizures Bicuculline Kainate Cephazolin Abstract The effects of interleukin-2 (IL-2) on various models of experimental epilepsy were studied after intracerebroventricular administration in DBA/2 mice, a strain genetically susceptible to sound-induced seizures. Convulsions were induced by physical stimulus (sound of 109 dB, 12-16 kHz) or by chemical ...