Running title: DiDonato et al.; Artery wall apoA1 is dysfunctional and not in HDL In In Inst st sti it itut te; e; ; 5 5 De Dept pt pt o of Cardiovascular Medicine, H H Hea a art and Vascul lar a a Ins nsti ti titu tute, Cleveland Clinic, D De Dept pt pt o o of f f Ch Ch Chem em emis is i t tr t y; 4 e De D pt o of f f Ma Math th them em e atic ic cs, s C C Cleve e ela a and Sta tate te e U U U...

The sequence requirements for transcriptional stimulation of the adenovirus major late promoter (MLP) by the products of the early transcription unit Ela and by the replication of viral DNA were analyzed by in vitro transcription. Sequences upstream of +33 are involved in the moderate Ela-responsiveness of the MLP, while sequences between +33 and +131 are required for its major replication-indu...

A key step in the de novo formation of the embryonic vasculature is the migration of endothelial precursors, the angioblasts, to the position of the future vessels. To form the first axial vessels, angioblasts migrate towards the midline and coalesce underneath the notochord. Vascular endothelial growth factor has been proposed to serve as a chemoattractant for the angioblasts and to regulate t...

Abstract —A motion adaptive deinterlacing algorithm is presented in this paper. It consists of the ELA-Median directional interpolation, same-parity 4-field horizontal motion detection, morphological operation for noise reduction and adaptive threshold adjusting. The edges can be sharper when the ELA-Median directional interpolation is adopted. The same-parity 4-field horizontal motion detectio...

CD8(+) T-cells specific for MART-1-(26-35), a dominant melanoma epitope restricted by human leukocyte antigen (HLA)-A*0201, are exceptionally common in the naive T-cell repertoire. Remarkably, the TRAV12-2 gene is used to encode the T-cell receptor alpha (TCRalpha) chain in >87% of these T-cells. Here, the molecular basis for this genetic bias is revealed from the structural and thermodynamic p...

Several studies have shown that vineyards are spatially variable at within field scale. Characterizing this variability could be used to improve grape and wine production, by adapting management practices and harvesting to the vineyard variability. The goal of this work is to calibrate a spatial model by coupling high quality, high cost punctual vine measurements with low cost medium-high densi...

The Study of Women's Health Across the Nation (SWAN) is a multiethnic cohort study of middle-aged women enrolled at seven US sites. A subset of 848 women completed a substudy in which their urinary gonadotropins and sex steroid metabolites were assessed during one complete menstrual cycle or up to 50 consecutive days. Urine was analyzed for LH, FSH, estrone conjugates (E1c), and pregnanediol gl...