Since nitric oxide (NO) plays a critical role in many biological processes, its precise detection is essential toward an understanding of its specific functions. Here we report on a facile and environmentally compatible strategy for the construction of an electrochemical sensor based on reduced graphene oxide (rGO) and AuPt bimetallic nanoparticles. The prepared nanocomposites were further empl...

A novel selective and sensitive electrochemical sensor for insulin detection has been fabricated and investigated. The electrochemical sensor was made from a mixture of silica gel, chitosan and nickel hydroxide (Ni(OH)2) nanoparticles, which was mounted on a silver wire and covered by a glass tube (silica gel/chitosan/Ni(OH)2 nanoparticles paste electrode). The sensor was characterized using cy...

For this paper, a fully integrated and highly miniaturized electrochemical sensor was designed and fabricated on a silicon substrate. A solvothermal-assisted reduced graphene oxide named "TRGO" was then successfully micro-patterned using a lithography technique, followed by the electrodeposition of bismuth (Bi) on the surface of the micro-patterned TRGO for the electrochemical detection of heav...

Electrochemical sensors are widely used for rapid and accurate measurement of blood glucose and can be adapted for detection of a wide variety of analytes. Electrochemical sensors operate by transducing a biological recognition event into a useful electrical signal. Signal transduction occurs by coupling the activity of a redox enzyme to an amperometric electrode. Sensor specificity is either a...

This paper reports the characterization of an electrochemical biosensor for the continuous monitoring of Naproxen based on cytochrome P450. The electrochemical biosensor is based on the drop-casting of multi-walled carbon-nanotubes (MWCNTs) and microsomal cytochrome P4501A2 (msCYP1A2) on a graphite screen-printed electrode (SPE). The proposed biosensor was employed to monitor Naproxen (NAP), a ...

graphene modified glassy carbon electrodes have been developed for the determination of calcium dobesilate in pharmaceutical formulations. the prepared graphene and cnts were used as a conductive substrate for electrochemical study of calcium dobesilate. the direct electrochemistry of calcium dobesilate showed a reversible cyclic voltammogram with a formal potential of 133 mv (vs. ag/agcl) for ...

A new sensitive, selective and nonexpensive electrochemical sensor was developed for electrocatalyticdetermination of glutathione (GSH)in pharmaceutical and biological samples. GSH is a tripeptide thiol present in all eukaryotic and probiotic cells. A voltammetric studyof GSH has been carried out at the surface of carbon paste electrode modified with multiwall carbon nanotubes(MWCNTPE) in the p...

Screening of colorectal cancer is crucial for early stage diagnosis and treatment. Detection of volatile organic compounds (VOCs) of the metabolome present in exhaled breath is a promising approach to screen colorectal cancer (CRC). Various forms of volatile organic compounds (VOCs) that show the definitive signature for the different diseases including cancers are present in exhale breathe. Am...

A simple, but highly sensitive, electrochemical sensor for the determination of salvianic acid A sodium (SAS) based on reduced graphene oxide (rGO) is reported. The sensor (rGO/GCE(ox)) was prepared by coating an rGO film on the surface of a pre-anodized glassy carbon electrode (GCE(ox)) through a dipping-drying method. The characteristic of the modified electrode was examined by scanning elect...