Interleukin 3 (IL-3) is a hematopoietic stem-cell growth and differentiation factor that is expressed solely in activated T and NK cells. Studies to date have identified elements 5' to the IL-3 coding sequences that regulate its transcription, but the sequences that confer T cell-specific expression remain to be clearly defined. We have now identified DNA sequences that are required for T cell-...

Previous studies have reported that extremely low-frequency electromagnetic fields (ELF-EMF) can affect the processes of brain development, but the underlying mechanism is largely unknown. The proliferation and differentiation of embryonic neural stem cells (eNSCs) is essential for brain development during the gestation period. To date, there is no report about the effects of ELF-EMF on eNSCs. ...

BACKGROUND Atherogenic effects of ELF-MF exposure have not been studied well so far. Therefore we have hypothesized that ELF-MF exposure might have atherogenic effect by impairing antioxidant function and increasing lipid peroxidation. This study was therefore undertaken to examine the effects of ELF-MF on paraoxonase (PON) activity, antioxidant capacity and lipid peroxidation metabolites. Effe...

This study examines English textbooks used in Taiwanese junior high schools (Grades 7 to 9) from the perspective of as a lingua franca (ELF) and with regard national curriculum. In this study, that are currently Taiwan were examined based on an analysis framework featuring ELF attributes. These attributes proposed enumerated light previous studies revealed partially reflected manifestation diff...

The extremely low frequency (ELF) radiation from various laptops and monitors model was investigated using a cell sensor manufactured by Action Electronic, USA that is optimized to measure radiofrequency and extremely low frequency radiation. The ELF measured vary between 0.05 and 2.5 mG for all the laptops/monitors studied however, Hp Pavilion dv6000 laptop was considered to emit highest ELF i...

External magnetic fields (MFs) have the ability to modify motor activity of animals, complex type of behaviour connected with dopaminergic and serotonergic neurotransmissions in the brain. Thus, the purpose of this study was to examine MF-induced changes in the activity of serotonin 5-HT(2A) receptors in the prefrontal cortex, as well as dopamine D(1) and D(2) receptors in the striatum of adult...

[1] ELF/VLF radio waves (300 Hz–30 kHz) are difficult to generate with practical antennae, because of their extraordinarily long (10–1000 km) wavelengths, and the lossy nature of the Earth’s surface at these frequencies. ELF/VLF waves have been successfully generated via amplitude modulated (AM) HF (2–10 MHz) heating of the lower ionosphere. Through the temperature-dependent conductivity of the...

Reactive oxygen species (ROS) are mediators of chronic tissue damage and fibrosis. Endogenous antioxidants may increase in response to oxidants and reduce tissue injury. We investigated the antioxidant response of the lungs to the chronic release of ROS, as occurs in the immune-specific granulomatous inflammation of chronic beryllium disease (CBD), and compared it with that in healthy controls ...

Assessment of liver fibrosis is important in determining prognosis, disease progression and need for treatment in patients with chronic hepatitis B (CHB). Limitations to the use of liver biopsy in assessing fibrosis are well recognized, and noninvasive tests are being increasingly evaluated including transient elastography (TE) and serum markers such as the Enhanced Liver Fibrosis (ELF) test. W...

Natural substrates of human leukocyte elastase (ELF) in the blood are suspected to be fibrinogen and fibrin, although ELF is immediately complexed with a2-macroglobulin (a2M) and other inhibitors. However, the enzymatic activity of a2M ELP complex is not yet clear. This study was undertaken t o clarify the activity of the complex. (1) ELF and a2M were purified respectively, then the a2MOELP com...