نتایج جستجو برای: endocrine

تعداد نتایج: 45244  

Journal: :The Lancet 2009
Anders Widmark Olbjørn Klepp Arne Solberg Jan-Erik Damber Anders Angelsen Per Fransson Jo-Åsmund Lund Ilker Tasdemir Morten Hoyer Fredrik Wiklund Sophie D Fosså

BACKGROUND Several studies have shown the efficacy of endocrine therapy in combination with radiotherapy in high-risk prostate cancer. To assess the effect of radiotherapy, we did an open phase III study comparing endocrine therapy with and without local radiotherapy, followed by castration on progression. METHODS This randomised trial included men from 47 centres in Norway, Sweden, and Denma...

Journal: :AACN clinical issues 2006
Tara Trimarchi

The endocrine system maintains a delicate balance of physiologic processes including growth and sexual maturation, energy production and utilization, fluid and electrolyte balance, and circulatory function. Although endocrine regulation of growth and sexual maturation is a significant issue in general pediatrics, disorders of energy production and utilization, fluid and electrolyte balance, and...

2010
Leonard Sax

BACKGROUND Recent reports suggest that endocrine disruptors may leach into the contents of bottles made from polyethylene terephthalate (PET). PET is the main ingredient in most clear plastic containers used for beverages and condiments worldwide and has previously been generally assumed not to be a source of endocrine disruptors. OBJECTIVE I begin by considering evidence that bottles made fr...

Journal: :The Yale Journal of Biology and Medicine 1967
Patrick J. Mulrow

of some of the preparative techniques available, the author describes a number of problems in molecular biology. The topics are well selected and include the plasma membrane, mitochondria, DNA, bacteria, and bacteriophages. The emphasis is placed on the subject or problem, with concise summaries of the information gained from use of the electron microscope. As a result, the book is informative ...

2016
Dudley Scott H. K. Lewis Leonard Williams

This is a delightful little book that should be in the hands of every practitioner, and Dr. Scott is to be congratulated in that he lias not only summarised the recent massive literature of the subject, but has done it in a readable manner, with a deep and earnest conviction that in these glands and in their correct use we have nature's own remedies for the many complications and symptoms of di...

Journal: :Endocrine-Related Cancer 2017

2015
Andrew Stone Elena Zotenko Warwick J. Locke Darren Korbie Ewan K. A. Millar Ruth Pidsley Clare Stirzaker Peter Graham Matt Trau Elizabeth A. Musgrove Robert I. Nicholson Julia M. W. Gee Susan J. Clark

Expression of oestrogen receptor (ESR1) determines whether a breast cancer patient receives endocrine therapy, but does not guarantee patient response. The molecular factors that define endocrine response in ESR1-positive breast cancer patients remain poorly understood. Here we characterize the DNA methylome of endocrine sensitivity and demonstrate the potential impact of differential DNA methy...

2012
Cornelis J. Lips Koen M. Dreijerink Jo W. Höppener

Multiple endocrine neoplasia type 1 is an inherited endocrine tumor syndrome, predominantly characterized by tumors of the parathyroid glands, gastroenteropancreatic tumors, pituitary adenomas, adrenal adenomas, and neuroendocrine tumors of the thymus, lungs or stomach. Multiple endocrine neoplasia type 1 is caused by germline mutations of the multiple endocrine neoplasia type 1 tumor suppresso...

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