نتایج جستجو برای: endocrine disruptor chemicals

تعداد نتایج: 87723  

Journal: :Integrated Environmental Assessment and Management 2016

Journal: :Chemosphere 2008
R Planelló J L Martínez-Guitarte G Morcillo

Bisphenol A (BPA) is an endocrine disruptor that can mimic the action of estrogens by interacting with hormone receptors and is, therefore, potentially able to influence reproductive functions in vertebrates. Although information about the interaction with the endocrine systems in invertebrates is limited, it has also been shown its effect on reproductive and developmental parameters in these o...

Journal: :Environment international 2016
Hong-Jie Sun Ping Xiang Jun Luo Huachang Hong Hongjun Lin Hong-Bo Li Lena Q Ma

Due to its toxicity as a carcinogen and wide distribution in the environment, arsenic (As) exposure in humans is of public concern globally. Many studies have manifested that As exposure induces cancers besides pathological effects in humans. Animal studies showed that chronic As exposure induces serious neurological effects. Based on recent studies, researchers proposed that As, including arse...

Journal: :Fertility and sterility 2011
Victor Y Fujimoto Dongsul Kim Frederick S vom Saal Julie D Lamb Julia A Taylor Michael S Bloom

Bisphenol A (BPA) is an endocrine disruptor with estrogenic properties that can adversely affect meiotic spindle assemblies. Our data indicate that BPA exposure in female patients may interfere with oocyte quality during IVF, as suggested by the inverse association between serum unconjugated BPA concentration and normal fertilization.

2012
Miriam Rosenbaum Matthew T. Agler Jeffrey J. Fornero Arvind Venkataraman Largus T. Angenent

Traditionally, wastewater treatment has been a combination of physical, biological, and chemical treatment methods. Physical methods of treatment include settling and sand filtration, biological methods include aerobic activated sludge, denitrification, and anaerobic digester treatment systems, while chemical methods include phosphate removal, dye and endocrine disruptor removal, and disinfecti...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2006
Susan C Laws S Yavanhxay Ralph L Cooper J Charles Eldridge

This study was conducted to characterize the estrogen receptor (ER)-binding affinities of 50 chemicals selected from among the high production volume chemicals under the U.S. EPA's (U.S. Environmental Protection Agency's) Toxic Substances Control Act inventory. The chemicals were evaluated using the rat uterine cytosolic (RUC) ER-competitive binding assay, with secondary analysis using Lineweav...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2013
Sarah Y Skolness Chad A Blanksma Jenna E Cavallin Jessica J Churchill Elizabeth J Durhan Kathleen M Jensen Rodney D Johnson Michael D Kahl Elizabeth A Makynen Daniel L Villeneuve Gerald T Ankley

Conazoles are designed to inhibit cytochrome P450 (CYP) 14α-demethylase, an enzyme key to fungal cell wall formation. In vertebrates, conazoles may inhibit other CYPs, potentially disrupting processes like sex steroid synthesis. Propiconazole is a current-use pesticide that is among the first chemicals being tested in the U.S. Environmental Protection Agency endocrine disruptor screening progra...

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