Objective(s): The purpose of this study was to detect the protective effects of adiponectin on coagulation dysfunction and its mechanism in sepsis of rats.Materials and Methods: The experimental samples were composed of sham group,   model group that was underwent cecal ligation and puncture (CLP) and three adiponectin treatment groups that treated by adiponectin with different dose (72 μg/kg, ...

OBJECTIVES To investigate visual outcome and postoperative complications in patients undergoing Descemet membrane endothelial keratoplasty with graft failure after penetrating keratoplasty. MATERIALS AND METHODS A retrospective analysis was performed with 5 patients who underwent Descemet membrane endothelial keratoplasty after failed penetrating keratoplasty. Intraoperative and postoperative...

purpose: to evaluate the effect of vacuum and flow rate on endothelial cell loss after high versus low vacuum phacoemulsification. methods: this randomized clinical trial was performed on 60 eyes of 60 patients with moderate lens opacity (nuclear sclerosis 3+). all surgeries were performed by one experienced surgeon using stop and chop technique with sovereign white star machine (amo). patients...

OBJECTIVE To evaluate the mean changes in Central Corneal Thickness (CCT) and Endothelial Cell Count (ECC) in eyes after pediatric cataract surgery with foldable intraocular lens using scleral tunnel incision micro-surgical technique. STUDY DESIGN Qausi experimental study. PLACE AND DURATION OF STUDY Department of Pediatric Ophthalmology and Strabismus, Al-Shifa Trust Eye Hospital, Rawalpin...

AIMS Tumour angiogenesis is essential for carcinogenesis and facilitates the process of tumour development and metastasis. Vascular endothelial growth factor (VEGF) is a well characterised angiogenetic factor and is known to play a crucial role in new vessel development. To gain further insight into the effects of microvessel density and VEGF expression in colon cancer, their relation with tumo...

Background: Exposure to environmental toxins such as organophosphates poses a great threat to the health of the public. In this work, we investigated the effects of continuous exposure to dichlorvos (DDVP) on kidney function and hematological parameters, and the possible antidote activity of Nigella sativa oil (NSO). Methods: This research was conducted in 2016, at The Animal Holding and Resea...

Objectives: To compare corneal endothelial cell changes namely, endothelial cell density (ECD), percentage polymegathism (CV) and pleomorphism (6A) along with central corneal thickness (CCT) in patients of type 2 diabetes mellitus with normal age and sexmatched subjects. To correlate corneal endothelial changes with diabetic retinopathy status, total duration of disease and glycemic control (Hb...

PURPOSE To evaluate the effects of prophylactic laser peripheral iridotomy on corneal endothelial cell density and cell morphology in subjects with primary angle closure suspect (PACS) within a one-year follow-up period. METHODS In this quasi-experimental prospective study, from June 2012 to November 2013, thirty-five PACS eyes underwent laser peripheral iridotomy at clinics affiliated to Shi...

We have previously shown that platelet-derived endothelial cell growth factor (PD-ECGF) is associated with angiogenesis of human colon cancer; this factor is expressed at high levels in vascular tumors that express low levels of vascular endothelial growth factor (VEGF). In these colon cancers, the major source of PD-ECGF is the infiltrating cells. In this study, we examined the role of PD-ECGF...

Introduction The continuous and rapid growth of telecommunication industries, along with the common application of cell phones, hasraised debates on the associated risks for humanhealth due to exposure to radiofrequency fields, caused bycell phonesorother sources, and industrial and medical applications. Accordingly, in this study, we aimed to investigate the effects of cell phone radiation on ...