نتایج جستجو برای: endothelial nitric oxide synthase
تعداد نتایج: 351879 فیلتر نتایج به سال:
PURPOSE Rocuronium bromide is a nondepolarizing neuromuscular blocking drug and has been used as an adjunct for relaxation or paralysis of the skeletal muscles, facilitation of endotracheal intubation, and improving surgical conditions during general anesthesia. However, intravenous injection of rocuronium bromide induces injection pain or withdrawal movement. The exact mechanism of rocuronium ...
BACKGROUND AND PURPOSE Endothelial nitric oxide synthase produces superoxide under physiological conditions leading to hydrogen peroxide (H(2)O(2)) -dependent dilations to acetylcholine in isolated mouse cerebral arteries. The purpose of this study was to investigate whether H(2)O(2) was involved in flow-mediated dilation (FMD). METHODS Cerebral arteries were isolated from 12+/-2-week-old C57...
ACTH = adrenocorticotrophic hormone; ARDS = acute respiratory distress syndrome; CO = cardiac output; CT = computed tomography; CVP = central venous pressure; CVVHF = continuous venovenous haemofiltration; eNOS = endothelial nitric oxide synthase; ICU = intensive care unit; LPS = lipopolysaccharide; NO = nitric oxide; PAWP = pulmonary artery wedge pressure; PEEP = positive end-expiratory pressu...
OBJECTIVE Cortactin translocates to the cell periphery in vascular endothelial cells (ECs) on cortical-actin assembly in response to pulsatile shear stress. Because cortactin has putative sites for AMP-activated protein kinase (AMPK) phosphorylation and sirtuin 1 (SIRT1) deacetylation, we examined the hypothesis that AMPK and SIRT1 coregulate cortactin dynamics in response to shear stress. AP...
Striatin is a protein regulator of vesicular trafficking in neurons that also binds caveolin-1 and Ca(2+)-calmodulin and could activate endothelial nitric oxide synthase. We have shown that striatin colocalizes with the mineralocorticoid receptor and that mineralocorticoid receptor activation increases striatin levels in vascular cells. To test whether striatin is a regulator of vascular functi...
INTRODUCTION Haemorrhagic shock is associated with an inflammatory response consecutive to ischaemia-reperfusion (I/R) that leads to cardiovascular failure and organ injury. The role of and the timing of administration of hydrogen sulphide (H2S) remain uncertain. Vascular effects of H2S are mainly mediated through K+ATP-channel activation. Herein, we compared the effects of D,L-propargylglycine...
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