The enteric nervous system (ENS) is essential for digestive function and gut homeostasis. Here we show that the amorphous neuroglia networks of the mouse ENS are composed of overlapping clonal units founded by postmigratory neural crest-derived progenitors. The spatial configuration of ENS clones depends on proliferation-driven local interactions of ENS progenitors with lineally unrelated neuro...

It is recognised that the enteric nervous system (ENS) has a unique ability to mediate reflex activity independently of input from the brain or spinal cord. This ability implies that the ENS contains sensory receptors, primary aVerent neurones, interneurones, and motor neurones. The events that are controlled, at least in part, by the ENS are multiple and include motor activity, secretion, abso...

The involvement of SOX10 and ZFHX1B in Waardenburg-Hirschsprung disease (hypopigmentation, deafness, and absence of enteric ganglia) and Mowat-Wilson syndrome (mental retardation, facial dysmorphy and variable congenital malformations including Hirschsprung disease) respectively, highlighted the importance of both transcription factors during enteric nervous system (ENS) development. The expres...

OBJECTIVES/HYPOTHESIS Empty nose syndrome (ENS) is often associated with psychological symptoms. With the absence of psychiatric instruments utilized in the current literature, the assessment of psychological disorder is limited, and the effectiveness of surgical intervention in improving such disorders in ENS are not well understood. The aim of this study was to evaluate the change in depressi...

UNLABELLED Elucidation of the cellular identity of neuronal precursors provides mechanistic insights into the development and pathophysiology of the nervous system. In the enteric nervous system (ENS), neurogenesis persists from midgestation to the postnatal period. Cellular mechanism underlying the long-term neurogenesis in the ENS has remained unclear. Using genetic fate mapping in mice, we s...

BACKGROUND AND AIMS The enteric nervous system (ENS) plays a crucial role in the control of gastrointestinal motility, secretion and absorption functions. Immunohistochemistry has been widely used to visualize neurons of the ENS for more than two decades. Genetically engineered mice that report specific proteins can also be used to visualize neurons of the ENS. The goal of our study was to deve...

The emerging edge computing (EC) paradigm promises to provide low latency and ubiquitous computation numerous mobile Internet of Things (IoT) devices at the network edge. How efficiently allocate geographically distributed heterogeneous resources a variety services is challenging task. While this problem has been studied extensively in recent years, most previous work largely ignored preference...

This research is motivated by the basic concept that humans are never satisfied in anything, because as creatures of homo sapiens, animal educandum, ens metaphysicum, and religious always experience a process. As thinking beings (homo sapiens) think, students (animal educandum) learn everything, philosophical (ens metaphysics) do not accept raw knowledge received, religious) have confidence. Cu...

Carbon sources in the Beaufort Sea revealed by molecular lipid biomarkers and compound specific isotope analysis I. Tolosa, S. Fiorini, B. Gasser, J. Martı́n, and J. C. Miquel International Atomic Energy Agency – Environment Laboratories, 4, quai Antoine 1er, MC 98000, Monaco Instituto de Ciencias del Mar, CSIC, Paseo Maŕıtimo de la Barceloneta, 37–49, 08003 Barcelona, Spain now at: Ecole Normal...