The tree tomato (Solanum betaceum Cav.) is an underutilized fruit crop native to the Andean region and phylogenetically related potato. Tree fruits have a high amount of nutrients bioactive compounds. However, so far there are no studies at genome or transcriptome level for this species. We performed de novo assembly annotation purple-fruited (A21) orange-fruited (A23) accessions. A total 174,2...

BACKGROUND: Metastasis regularly is a marker of the disease development cancers. Some metastatic sites significantly showed more serious clinical outcomes in non-small cell lung cancer (NSCLC). Whether they are caused by tissue-specific (TS) or non-tissue-specific (NTS) mechanisms still unclear. OBJECTIVE: Explore co-expression gene modules metastases. METHODS: Weighted Correlation Network Anal...

In this paper, we present a methodology for ontology evolution, by focusing on the specific case of multimedia ontology evolution. In particular, we discuss the situation where the ontology needs to be enriched because it does not contain any concept that could be used to explain a new multimedia resource. The paper shows how ontology matching techniques can be used to enforce the discovery of ...

Salt injury, as an abiotic stress factor, seriously affects the quality and yield of crops. This study was conducted by analyzing alternative splicing in control (CK), δ-aminolevulinic acid (ALA), NaCl, ALA + NaCl treatments wild jujube (Zizyphus spinosus (Bunge)Hu) using RNA-seq. It found that unique differential is closely related to alleviation salt analyzed intermediates chlorophyll synthes...

Abstract To explore the adaptation mechanism of Hainan medaka, Oryzias curvinotus , to salinity, this study performed a histological and RNA‐Seq comparative analysis female medaka liver with different salinities (0, 15 30 practical salinity unit [psu]). In psu group, volume hepatocytes was increased cytoplasmic fat accumulated. A total 83,758 unigenes were assembled by RNA‐Seq, which 31,147 ann...

Most methods for large-scale gene expression microarray and RNA-Seq data analysis are designed to determine the lists of genes or gene products that show distinct patterns and/or significant differences. The most challenging and rate-liming step, however, is to determine what the resulting lists of genes and/or transcripts biologically mean. Biomedical ontology and pathway-based functional enri...

During the attack of a pathogen, variety defense-associated proteins are released by host plant in apoplast to impede perceived attack. This study utilized mass spectrometry (LC-MS/MS) and label-free quantification method analyze apoplastic fluid (APF) from maize stalk identified responsive Fusarium verticillioides infection. We have 742 proteins, among these, 119 were differentially accumulate...

The present study aimed to elucidate key molecular mechanisms in the progression of diffuse intrinsic pontine glioma (DIPG). The gene expression profile GSE50021, which consisted of 35 pediatric DIPG samples and 10 normal brain samples, was downloaded from the Gene Expression Omnibus database. The differentially-expressed genes (DEGs) in the pediatric DIPG samples were identified. Gene Ontology...

Abstract Background Cervical cancer (CC) is one of the most common gynaecological malignancies all around world. The mechanisms cervical carcinoma formation remain under close scrutiny. long non-coding RNAs (lncRNA) and microRNAs (miRNAs) play important roles in controlling gene expression promoting development progression by acting as competitive endogenous RNA (ceRNA). However, lncRNA associa...

Ontology maturing as a conceptual process model is based on the assumption that ontology engineering is a continuous collaborative and informal learning process and always embedded in tasks that make use of the ontology to be developed. For supporting ontology maturing, we need lightweight and easy-to-use tools integrating usage and construction processes of ontologies. Within two applications ...