The realization of physiologically-relevant advanced in vitro models is not just related to the reproduction of a three-dimensional multicellular architecture, but also to the maintenance of a cell culture environment in which parameters, such as temperature, pH, and hydrostatic pressure are finely controlled. Tunable and reproducible culture conditions are crucial for the study of environment-...

What is a UML sequence diagram? UML sequence diagrams are used to represent or model the flow of messages, events and actions between the objects or components of a system. Time is represented in the vertical direction showing the sequence of interactions of the header elements, which are displayed horizontally at the top of the diagram. Sequence Diagrams are used primarily to design, document ...

In system development life cycle (SDLC), a system model can be developed using Data Flow Diagram (DFD). DFD is graphical diagrams for specifying, constructing and visualizing the model of a system. DFD is used in defining the requirements in a graphical view. In this paper, we focus on DFD and its rules for drawing and defining the diagrams. We then formalize these rules and develop the tool ba...

We analyze traffic data from a highway section containing one effective on-ramp. Based on two criteria, local velocity variation patterns and expansion (or nonexpansion) of congested regions, three distinct congested traffic states are identified. These states appear at different levels of the upstream flux and the on-ramp flux, thereby generating a phase digram of the congested traffic flow. O...

We consider separation of ideal multicomponent mixtures with constant relative volatilities and constant molar flows and at constant pressure. The exact analytical solution of minimum energy in a generalized Petlyuk arrangement for separation of N-component feed into M products has been derived. Interestingly, the minimum-energy solution in a complex integrated Petlyuk arrangement is equal to t...

Systematic studies of global observables in different collision systems are indispensable for mapping the QCD phase diagram. Fluctuations in these quantities can provide fundamental information relevant for the phase transitions. The following global observables relevant to critical behavior are studied: the longitudinal density correlation, K to π and p to π fluctuations, and the constituent q...

license-info) in effect on the date of publication of this document. Please review these documents carefully, as they describe your rights and restrictions with respect to this document. Abstract This document gives example call flows of race conditions in the Session Initiation Protocol (SIP). Race conditions are inherently confusing and difficult to thwart; this document shows the best practi...

Ring-diagram analysis is a technique of local helioseismology used to infer plasma flows in the solar convection zone which generates intermediate data products known as ring-fitting parameters. Knowing the sensitivity of ringfitting parameters to actual flows in the Sun is important for interpreting these measurements.Working in plane-parallel geometry, we compute the linear sensitivity of rin...

Original scientific paper Planning of road transport infrastructure is a complex process. One of the major issues is determining the design elements of road infrastructure (road type and number of traffic lanes, cross-sectional profile, etc.). When designing roads, parameters from the international literature are used, containing values derived empirically from local data on traffic flow (mostl...

This work is an extension of PedCTM, an aggregate and transient cell transmission model for multidirectional pedestrian flows in which pedestrian characteristics are assumed to be homogeneous across the population considered. Critically, one fundamental diagram relating pedestrian speed and flow to local pedestrian density is employed across the entire population. This work extends the model to...