Modular design, Axiomatic design (AD) and Theory of inventive problem solving (TRIZ) have been increasingly popularized in concept modern mechanical product. Each method has their own advantages drawbacks. The benefit modular is reducing the product period, AD capability analysis, while TRIZ’s expertise innovative idea generation. According to complementarity these three approaches, an systemat...

BACKGROUND Development of the epidermal permeability barrier (EPB) is essential for neonatal life. Defects in this barrier are found in many skin diseases such as atopic dermatitis. OBJECTIVE We investigated the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the development and function of the EPB. METHODS Timed-pregnant C57BL/6J mice were gavaged with corn oil or TCDD (10 μg/kg b...

Shield tunnels will inevitably pass through viaduct piles at a close distance due to the extensive construction of subways and viaducts in city. In order understand influence shield tunneling on deformation existing pile foundation grouting protection measures, based an engineering case, Changsha Metro Line 5 (from South Gaoqiao station Guitang station), three-dimensional finite element model w...

The `Eastern Paci¢c Barrier' (EPB), 5400 km of uninterrupted deep water between the central and eastern Paci¢c, constitutes the greatest marine obstacle to the dispersal of shallow-water organisms. However, some species are found on both sides of the EPB.These `transpaci¢c' species are considered by `dispersal' biogeographers as evidence of invasions through the barrier. `Vicariance' biogeograp...

To develop new photoinduced electron-transfer (PET) reagents, we established a method for predicting the fluorescence quantum yields (phi) of the benzofurazan compounds bearing an aliphatic substituent group having an n-electron. The PET process occurred sufficiently to reduce the phi values in the benzofurazan compounds bearing an aliphatic moiety, which had a high quenching ability. The quenc...

−This paper describes a parallel model-based fault detection algorithm for an electronic parking brake (EPB) system, which consists of an electronic control unit with built-in current sensor and braking force sensor. For the EPB system to supply sufficient parking force to a vehicle, the parking force sensor is of utmost importance. If a fault occurs in this sensor, sufficient parking force may...

INTRODUCTION China's largest cities like Beijing and Shanghai have seen a sharp increase in subway network development as a result of the rapid urbanization in the last decade. The cities are still expanding their subway networks now, and many shield tunnels are being or will be constructed in close proximity to the existing operational subway tunnels. The execution plans for the new nearby shi...

Regarding the situation of slurry pressure shield tunneling underneath existing operating railway, traditional risk assessment method takes settlement railroad as evaluation objective cannot determine development trend. Therefore, a model based on set pair analysis was proposed. Firstly, according to Slurry Pressure Balance construction mechanism, source identification process and operation car...

CONTEXT The yield of in-hospital stool cultures performed more than 72 hours after admission is low, and a commonly used policy dictates that laboratories reject these cultures to save costs. However, enteropathogenic bacteria other than Clostridium difficile (EPB) may cause nosocomial illness that would be missed by use of such a "3-day rule." OBJECTIVE To develop guidelines for hospital use...