AIM This study was planned with the aim of retrospectively reviewing the clinical and laboratory findings and therapies of our patients diagnosed with tuberous sclerosis and redefining the patients according to the diagnostic criteria revised by the 2012 International Tuberous Sclerosis Complex Consensus Group and comparing them with the literature. MATERIALS AND METHOD Twenty patients diagno...

OBJECTIVE To assess factors associated with favorable seizure outcome after surgery for symptomatic epileptic spasms and improve knowledge on pathophysiology of this seizure type. METHODS Inclusion criteria were: (1) age between 6 months and 15 years at surgery; (2) active epileptic spasms; (3) follow-up after surgery >1 year. RESULTS We retrospectively studied 80 children (aged 1.3 ± 2 yea...

Hemifacial spasm is a socially disabling condition that manifests as intermittent involuntary twitching of the eyelid and progresses to muscle contractions of the entire hemiface. Patients receiving microvascular decompression of the facial nerve demonstrate an abnormal lateral spread response (LSR) in peripheral branches during facial electromyography. The authors retrospectively evaluate the ...

Rationale: A novel COVID-19 with a severe acute respiratory syndrome or pneumonia had arisen in Wuhan, China December 2019. Emerging atrial fibrillation patients is highly significant cardiovascular medicine. newly coronary artery spasm the presentation of infection has certainly risk impact on both morbidity and mortality patients. Wavy triple an electrocardiographic sign (Yasser Sign) innovat...

A 48-year-old man developed severe chest pain and became unconscious. Coronary cineangiography revealed single coronary artery of the type L2b by Sharbaugh and White. Ergonovine, 0.2 mg i.v., produced coronary arterial spasm in the right coronary artery. This case suggests that coronary arterial spasm might be a cause of sudden death in patients with single coronary artery. However, an associat...

Spasm of the near reflex, as first described by Cogan in 1955, is a triad of intermittent convergent strabismus, accommodative spasm, and pupillary miosis. The accommodative spasm induces pseudo-myopia that is usually accompanied by visual blurring. It is a functional disorder that has been attributed to hysteria, although it can have an organic etiology. Definitive treatment remains problemati...

the occurrence of neonatal seizures may be the first and perhaps, the only clinical sign of a central nervous system (cns) disorder in the newborn infant. identifying the etiology for the neonatal seizures is/critical to prognosis and treatment. the most common etiology for neonatal seizures is hypoxic-ischemic encephalopathy. seizures may indicate the presence of a potentially treatable etiolo...

Focal coronary spasm is often associated with an area of mural plaque disease. This report describes a patient with recurrent severe coronary spasm unresponsive to medical treatment. Coronary arteriography and intravascular ultrasound identified a candidate area of minor coronary atheromatous disease but ergonovine provocation testing showed the spastic coronary segment to be distal to and dist...

A prospective, interventional study was carried out on all the patients of Essential Blepharospasm Symdrome, Hemifacial Spasm and Meige’s syndrome who underwent treatment with botulinum toxin A in BP Koirala Lions Centre for Ophthalmic studies during a study period of one and half years. Pretreatment grading of the spasm was done with Jankovic spasm grading and post treatment response was seen ...

We injected acetylcholine (ACh), the neurotransmitter of the parasympathetic nervous system, into the coronary arteries of 28 patients with variant angina. Injection of 10 to 80 micrograms ACh into the coronary artery responsible for the attack induced spasm together with chest pain and ST segment elevation or depression on the electrocardiogram in 30 of the 32 arteries of the 25 of the 27 pati...