The most widely employed industrial process for producing alumina (Bayer process) involves the dissolution of available aluminium hydroxide minerals present in raw bauxite into high temperature sodium hydroxide solutions. On cooling of the solution, or liquor in the industrial vernacular, Al is precipitated from solution in the form of gibbsite (Al(OH)3). In order to optimise the process, a det...

A novel general approach was described to address many of the challenges of salt solubility determination of drug substances, with data processing and refinement of equilibrium constants encoded in the computer program pDISOLX TM . The new approach was illustrated by the determinations of the solubility products of diprenorphine hydrochloride, codeine hydrochloride and phosphate, lidocaine hydr...

The equilibrium solubility values and dissolution profiles in each of the media (FaSSIF or FaSSIF-V2) produced using methylene chloride and the corresponding SIF Powder are equivalent for the drugs tested representing acid, basic, and neutral compounds. Therefore, it is practical to switch from the more labor-intensive solvent-evaporation method to the use of standardized instant powders for pr...

Abstract Equilibrium solubility of triclocarban (TCC) expressed in mole fraction 1,4-dioxane and cyclohexane, as well, 19 {cyclohexane (1) + (2)} mixtures, was determined at seven temperatures from T = (288.15 to 318.15) K. Logarithmic TCC these cosolvent mixtures adequately correlated with a lineal bivariate equation function both the composition temperature. Apparent thermodynamic quantities ...

Large discrepancies in published neon and nitrogen solubility data limit the interpretation of oceanic measurements of these gases. We present new solubility measurements for neon, nitrogen and argon in distilled water and seawater, over a temperature range of 1–30 oC. Water was equilibrated with air at measured temperatures, salinities and pressures. Dissolved Ne concentrations were then deter...

A study of the high-pressure phase equilibria in the ternary system oleic acid/1octanol/supercritical CO2 was performed to obtain information for optimization of enzymatic synthesis of n-octyl oleate. Equilibrium data were measured at temperatures of 308.15, 323.15 and 343.15 K over a pressure range from 1 to 25 MPa. Two different apparatuses: a Variable Volume View Cell and a Batch Stirred Tan...