A 39-year-old otherwise healthy woman presented to our dermatology clinic with a two-week history of a swelling and pain on her neck. She noted a low-grade fever and malaise for ten days. The patient reported no history of tick bite, new medication or consuming raw meat. Physical examination revealed fever (38.3°C), an enlarged, painful 4.5 x 4.8 cm sized lymphadenopathy in the right submandibu...

Leprosy reactions are acute inflammatory processes, immunologically mediated that may be precipitated by many factors, including infections and vaccines. They classified in Type 1 Reaction or Reversal Reaction, 2 (T2LR). The most common clinical manifestation of T2LR is the erythema nodosum (EN), and, because this, it also called Erythema Nodosum Leprosum (ENL). Reactions can occur before, duri...

OBJECTIVE To compare the occurrence, duration and severity of ENL in leprosy patients treated with either 12 or 24 months of standard multi-drug therapy (MDT). MATERIALS AND METHODS STUDY POPULATION 296 patients treated with MDT for 2 years, between 1985 and 1992 and followed up as part of a relapse study; and 293 patients, treated between 1998 and 2004, with MDT for 1 year and also follow...