This study was conducted to evaluate and compare the clinical, hemato-biochemical endoscopic aspects of gastropathy in dogs treated with meloxicam alone or incombination esomeprazole misoprostol. Twenty baladi healthy were included experimental study. Dogs divided into four groups each group consisting five animals; Group I (control group), that does not receive any medication. Meloxicam into: ...

We report the case of a 74-year-old woman with a history of hypertension, diabetes mellitus, dyslipidemia, spondyloarthritis, and idiopathic thrombocytopenic purpura for which she had undergone splenectomy 5 years previously. She was being followed up by her rheumatologist for joint pain of inflammatory origin with low titers of rheumatoid factor and was taking lorazepam, ranitidine, domperidon...

Objective CYP2C19 metabolic activity influences the efficacy of Helicobacter pylori eradication therapies comprising PPIs. Rabeprazole (RPZ) and esomeprazole (EPZ) are PPIs not extensively metabolized by CYP2C19. The aim of this study was to elucidate whether or not first-line triple therapies using RPZ or EPZ are equally effective in Japanese patients with different CYP2C19 genotypes. Methods ...

Objective: Selective serotonin reuptake inhibitors (SSRIs) induce some adverse effects on gastrointestinal system. We aimed to investigate the role of citalopram, a well-known SSRI, on the reflux symptoms. Methods: Seventy patients with gastro-oesophageal reflux disease (GERD) were included to the study. Anxiety and depressive symptoms were measured with the Beck Anxiety Inventory (BAI) and Bec...

Functional dyspepsia (FD) is a gastroduodenal disorder that presents as postprandial fullness, early satiation, or epigastric burning despite no evidence of a structural disease. Proton pump inhibitors (PPIs) are often the first choice for treating FD. However, some patients need additional medication because of residual symptoms despite a certain level of benefit from the PPI. For these patien...

Received: September 16, 2008. Accepted: December 24, 2008. Corresponding author: Young Kyoo Choi, M.D., Department of Anesthesiology and Pain Medicine, School of Medicine, Kyung Hee University, Hoegi-1dong, Dongdaemun-gu, Seoul 130-702, Korea. Tel: 82-2-958-8598, Fax: 82-2-958-8580, E-mail: [email protected] Copyright c Korean Society of Anesthesiologists, 2009 Effects of esomeprazole premedi...