BACKGROUND Pediatric eosinophilic esophagitis (EoE) is a newly recognized antigen-induced form of chronic esophagitis (CE). OBJECTIVE Characterization of long-term clinical outcomes in patients with pediatric EoE is needed. METHODS From histologic review of 3817 pediatric esophageal biopsy specimens from 1982-1999, we conducted a nested case-control study of patients with retrospectively id...

BACKGROUND Digestive damage due to Chagas disease (CD) occurs in 15-20% of patients diagnosed as a result of peristaltic dysfunction in some endemic areas. The symptoms of chronic digestive CD are non-specific, and there are numerous confounders. Diagnosis of CD may easily be missed if symptoms are not evaluated by a well trained physician. Regular tests, as barium contrast examinations, probab...

Lymphocytic esophagitis (LE) is a clinicopathologic entity first described by Rubio et al in 2006. It is defined as peripapillary intraepithelial lymphocytosis with spongiosis and few or no granulocytes on esophageal biopsy. This definition is not widely accepted and the number of lymphocytes needed to make the diagnosis varied in different studies. Multiple studies have described potential cli...

the patient is a 69 years old female presented with chest pain and rapidly progressive dysphagia. then she suffered of hematemesis and aphagia. in evaluation of patient, a intramural hematoma obstructing esophageal lumen was demonstrated which was accompanied with mucosal ulceration and bleeding. it appears that this complication occurred in the context of concomitant use of alendronate with as...

Introduction: The aim of this study was to assess the clinical profile of patients with benign strictures of middle and lower thirds of esophagus , to analyse the grade of dysphagia and site of stricture by barium swallow and to describe the endoscopic and histopathological findings in them Methods: It was a prospective, cross sectional, descriptive study where thirty patients with benign struc...

INTRODUCTION Upper airway nerve and muscle damage associated with obstructive sleep apnea may impair the strength and dynamics of pharyngeal and esophageal contractions during swallowing. OBJECTIVE To evaluate the presence of alterations in pharyngoesophageal manometry in patients with obstructive sleep apnea with and without oropharyngeal dysphagia. METHODS This study prospectively evaluat...

BACKGROUND In type 1 multiple endocrine neoplasia (MEN1), esophageal diseases association with excessive gastrin secretion in Zollinger-Ellison syndrome (ZES) sometimes develop. Here, we reported a case of MEN1/ZES, who developed dysphagia due to reflux esophagitis with severe esophageal stricture. Treatment for his esophageal stricture and ZES was discussed. CASE PRESENTATION A 43-year-old m...

BACKGROUND Esophageal dilation by rendezvous is a useful technique for the treatment of complicated esophageal strictures. METHODS AND RESULTS We present a case of a 74-year-old man with chronic dysphagia caused by a complete cervical esophageal stricture that developed after external beam radiotherapy for treatment of papillary thyroid carcinoma. During attempted dilation using the rendezvou...

Achalasia is characterized by incomplete lower esophageal sphincter (LES) relaxation and aperistalsis of the esophagus. It is manifested by regurgitation, dysphagia and weight loss. Treatment options include addition of pharmacotherapy, endoscopic dilatation, botulinum toxin injection (BTI) and surgical myotomy. The presence of esophageal varices makes endoscopic treatment difficult and therefo...