BACKGROUND AND PURPOSE Revascularization by coronary artery bypass graft (CABG) surgery or percutaneous coronary intervention (PCI) is frequently deferred in patients with chronic kidney disease (CKD) to avoid precipitating end-stage renal disease (ESRD), but reliable estimates of absolute and relative risks of death and ESRD after CABG and PCI are unavailable. METHODS AND RESULTS CKD patient...

BACKGROUND End-Stage Renal Disease (ESRD) is a worldwide public health problem. Currently, many genome-wide association studies have suggested a potential association between human leukocyte antigen (HLA) and ESRD by uncovering a causal relationship between HLA and glomerulonephritis. However, previous studies, which investigated the HLA polymorphism and its association with ESRD, were performe...

BACKGROUND Systemic lupus erythematosus (SLE) is a devastating systemic disease that can lead to end-stage renal disease (ESRD). Our goal was to assess the relative mortality risk associated with race in pediatric and adult populations with ESRD secondary to SLE maintained on hemodialysis (HD). METHODS We identified an inception cohort of patients who were started on HD in January 1990 from d...

The aim of our study was to estimate the risk of end-stage renal disease (ESRD) in type 1 diabetes mellitus (T1DM) in Taiwanese people; in addition, our goal was to determine how the age, year, and sex at registration of T1DM affects the risk. Population-based cohort study. A nationwide cohort study of 7203 Taiwanese patients with T1DM registered in 1999 to 2010 was followed up until ESRD, deat...

OBJECTIVE We examined the effect of intrauterine diabetes exposure (IDE) on the incidence of diabetic end-stage renal disease (ESRD) in Pima Indians with type 2 diabetes. RESEARCH DESIGN AND METHODS Individuals were followed from their first diabetic examination until December 2006, death, ESRD, or age of 45 years. RESULTS Among the 1,850 diabetic participants, 102 had IDE. ESRD developed i...

End-stage renal disease (ESRD) has been a widespread disease in many countries, especially in Taiwan. According to the statistics of United States renal data system (USRDS), Taiwan had high rates of incident ESRD and the greatest rates of prevalent ESRD in 2008. Moreover, with the increasing ESRD patients appear, the huge expense becomes a heavy burden in the society. To avoid deterioration, th...

Women with End Stage Renal Disease (ESRD) have hormonal imbalance leading to gynaecological and reproductive disturbances. The objective of this study was to see the reproductive and gynaecological problems associated with ESRD. Forty Saudi Arabian women with a diagnosis of ESRD for a period of 60 months were interviewed at the dialysis unit of King Fahd University Hospital, Al Khobar.The avera...

BACKGROUND Longer nephrology care before end-stage renal disease (ESRD) has been linked with better outcomes. METHODS We investigated whether longer pre-end-stage renal disease (ESRD) nephrology care was associated with lower mortality at both the patient and state levels among 443 761 incident ESRD patients identified in the USA between 2006 and 2010. RESULTS Overall, 33% of new ESRD patie...

BACKGROUND Limited evidence suggests that persons with end-stage renal disease (ESRD) may be at increased risk for malignancy. The appropriateness of screening procedures in this population has not been evaluated. OBJECTIVE To determine the relative cost-effectiveness of hypothetical cancer screening programs in the population with ESRD compared with the general population. METHODS We perfo...

BACKGROUND Polymorphisms in the non-muscle myosin IIA gene (MYH9) are associated with focal segmental glomerulosclerosis (FSGS) and non-diabetic end-stage renal disease (ESRD) in African Americans and FSGS in European Americans. We tested for association of single nucleotide polymorphisms (SNPs) in MYH9 with T2DM-ESRD in European Americans; additionally, three APOL1 gene variants were evaluated...