ion channels play a major role in the regulation of t cell function in health and disease. in a computer-based model, established to simulate t cells’ membrane potential (vm) generation, we discovered a discrepancy between the simulation and patch-clamp recordings. the predicted vm was more hyperpolarized than the measured vm, indicating that a yet unknown, depolarizing ion current might contri...

Modern smartphones are equipped with a number of embedded sensors, such as accelerometer, magnetometer, gyroscope, barometer, etc., and these sensors are increasingly being used in smartphone based localization. The most widely used smartphone based localization technique is Pedestrian Dead Reckoning (PDR) which leverages on the previous position, walking length and walking direction to determi...

in the last three decades investigations in the field of oxadiazoles have been intensified due to their diverse therapeutic uses. oxadiazole are well known to have a wide range of therapeutic activities namely anti-inflammatory, analgesic, antipyretic, anticonvulsant, antiparasitic, antimicrobial etc. in this study, we have evaluated the antimicrobial activity of some carboxymethyl derivatives ...

This paper describes the application of process integration principles to the design of oil refineries hydrogen network. In this regard, a design hierarchy as well as heuristics and required guidelines are proposed. The recommended rules compensate lack of procedure to the design and make the design process easier. The guiding principles of the design are based upon pinch technology and ext...

Signboards and billboards provide a challenge to image seg¬mentation methods, since these images may also have pictures and graphical objects, apart from text objects. Methods that often succeed in more traditional text block segmentation situations do not perform well here since estimation of text lines and character widths etc fail due to the short sample sizes. Further, extraction of charact...

though not directly relevant, if the volunteer rate was related in any way to previous poliomyelitis experience in the area. This was clearly a well-conducted experiment carried out in extremely difficult circumstances, but whether or not the younger group of children benefited from the vaccine to the same extent as the older group depends upon this question of bias.-I am, etc., London, W.C.1. ...

The substantial applicability of technological advancements to the healthcare sector and its allied segments are on verge questioning abilities hospitals, medical institutions, doctors clinical pathologists in delivering world class facilities global patient community. Investigative works pertinent role played motivated this work be undertaken. Part-I review addressed applicable play advanced t...

Ion channels play a major role in the regulation of T cell function in health and disease. In a computer-based model, established to simulate T cells’ membrane potential (VM) generation, we discovered a discrepancy between the simulation and patch-clamp recordings. The predicted VM was more hyperpolarized than the measured VM, indicating that a yet unknown, depolarizing ion current might ...