This discussion will highlight the following 9 specific points that related to metabolic acidosis caused by various toxins. The current recommendation suggests that alcohol dehydrogenase inhibitor fomepizole is preferred to ethanol in treatment of methanol and ethylene glycol poisoning, but analysis of the enzyme kinetics indicates that ethanol is a better alternative. In the presence of a mode...

SYNTHESIS 2006, No. 4, pp 0645–0653xx.xx.2006 Advanced online publication: 25.01.2006 DOI: 10.1055/s-2006-926313; Art ID: M05505SS © Georg Thieme Verlag Stuttgart · New York Abstract: Starting from glycidol, the synthesis of dimethoxytritylated glycol nucleoside phosphoramidites of adenine (A), thymine (T), uracil (U), guanine (G), and cytosine (C) is reported. These phosphoramidites are the bu...

creams used for atopic eczema in Birmingham, UK illegally contain potent corticosteroids. Arch Dis Child 2003;88:1056–7. 15 Geiling EMK, Cannon PR. Pathological effects of elixir of sulphanilamide (diethylene glycol) poisoning. JAMA 1938;111:919–26. 16 Okuonghae HO, Ighogboja IS, Lawson JO, et al. Diethylene glycol poisoning in Nigerian children. Ann Trop Paediatr 1992;12:235–8. 17 Hanif M, Mob...

THE USE of polyethylene glycol (PEG) in preservation solutions has been associated with a decreased incidence of rejection in clinical and experimental transplantation. Using the isolated perfused rat liver model, we found that PEG, when added to phosphate-buffered sucrose solution (PBSL), provided improved liver preservation. A direct comparison of three different molecular configurations of P...

patient developed occupational dermatitis from butylene glycol in a soap (9, 10). 2 large-scale group studies, including 364 and 272 patients, give frequencies of contact allergy to 1,3-butylene glycol of 0.4% and 1.1%, respectively, of patients tested (1, 2). Although 1,3-butylene glycol has been considered a safe cosmetic ingredient and a rare contact allergen, we suggest that allergy to it w...

INTRODUCTION Every year about 2.4 million people in USA are exposed to toxic substances. Many of them are children below 6 years of age. Majority of poisonings in children are incidental and related to household products including for example drugs, cleaning products or antifreeze products. Antifreeze solutions contain ethylene glycol and methanol. Treatment of these toxic substances involves e...

A microbial consortium (EG-c) capable of degrading high concentrations of glycol-based waste was isolated from soil enrichments. The isolate primarily responsible for glycol degradation was a gram-negative rod (EG-y) that produced a water-soluble pigment. Initial laboratory experiments measured the degradation of ethylene glycol (EG) and propylene glycol (PG) at 25OC. Cell biomass optical densi...

In this paper, the synthesis of novel divalent cationic lipids with poly(ethylene glycol) segments is described. The lipids consist of an unsaturated double-chain hydrophobic moiety based on 3, 4-dihydroxy benzoic acid, attached to a hydrophilic poly(ethylene glycol) spacer which contains a divalent cationic end group. As poly(ethylene glycol) spacers monodisperse triethylene glycol and teleche...

Linear alkyl ethoxylates (polyethylene glycol alkyl ethers) were fermented completely to methane and CO2 in enrichment cultures inoculated with anoxic sewage sludge. Long-chain fatty acids were released as intermediates. No degradation was found with polypropylene glycol and polypropylene glycol-containing surfactants. Two types of primary ethoxylate-degrading bacteria were isolated and charact...

We studied polyethylene glycol 6000 precipitation of lipoproteins other than high-density lipoproteins, before cholesterol is estimated in the supernate. Other lipoproteins in the supernatant fractions were detected by using rocket immunoelectrophoresis. A polyethylene glycol concentration of 75 g/L in the final mixture appeared to be optimal, and results agreed with those obtained by ultracent...