Direct comparison of human diseases with model phenotypes allows exploration of key areas of human biology which are often inaccessible for practical or ethical reasons. We review recent developments in comparative evolutionary approaches for finding models for genetic disease, including high-throughput generation of gene/phenotype relationship data, the linking of orthologous genes and phenoty...

on the basis of discourse grammar (dg), this study investigates the expression of  yæ'ni in persian. the term was originally borrowed from arabic and has undergone the process of grammaticalization. it exhibits different pragmatic functions to characterize changes involved in the evolution of this discourse marker. the study suggests that grammaticalization of yæ'ni should be analyzed...