نتایج جستجو برای: excessive erythrocytosis
تعداد نتایج: 54835 فیلتر نتایج به سال:
5–15 ng/ml). In May 1998, the patient developed post-renal-transplant erythrocytosis. Hb and Hct values rose to 19.4 g/dl and 54% respectively. WBC remained within
The mechanism by which angiotensin-converting enzyme inhibitors reduce red cell mass in renal transplant recipients with erythrocytosis is unclear. To examine the role of angiotensin II in this disorder, losartan (a competitive antagonist of the angiotensin II type 1 [AT1] receptor) was administered to 23 patients with erythrocytosis. Fourteen patients took 25 mg/d for 8 wk; nine others were tr...
BACKGROUND Phlebotomy is the most commonly treatment used for erythrocytosis and polycythaemia. After the introduction in the medical practice of cell separators, erythrocytapheresis has been also introduced. The aim of the study was to compare the clinical results of the two kinds of treatment. PATIENTS AND METHODS We analysed 98 patients affected by different forms of erythrocytosis, divide...
To further characterize JAK2 exon 12 mutations, we performed molecular screening in 409 patients with polycythemia vera or unclear erythrocytosis with unmutated JAK2V617. The frequency of JAK2exon12 mutations was 10/63 (15.9%) in PV but only 5/346 (1.4%) in the erythrocytosis cases. Nine different mutations including four new types (D544-L545del, H538DK539LI540S, H538-K539del, V536-F547dup) wer...
Angiotensin II exerts a mitogenic effect in several in vitro models, but a direct effect on erythroid progenitors has not been documented. Angiotensin-converting enzyme inhibitors and losartan, an angiotensin II type 1 receptor (AT1) antagonist, ameliorate posttransplant erythrocytosis, without altering serum erythropoietin levels. We studied erythroid differentiation and the effect of angioten...
BACKGROUND AND PURPOSE Patients suspected of having aneurysmal subarachnoid hemorrhage (SAH) are initially evaluated with noncontrast head computed tomography. If the computed tomography is negative, but clinical concern for SAH is high, a lumbar puncture with cerebrospinal fluid analysis is typically performed. The purpose of this study was to evaluate the accuracy of cerebrospinal fluid xanth...
I N A PREVIOUS STUDY, it was shown that erythrocytosis was present in 11.7 per cent of southern Chinese patients with hepatocellular carcinoma but that the mechanism of production remained obscure.’ Plasma erythropoiesis-stimulating factor ( ESF ), assayed on the fasted rat, was not increased in four subjects studied. Subsequent reports of the existence of erythrocytosis in hepatocellular carci...
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