Familial gigantiform cementoma is an exceedingly rare but distinct subtype of cemento-osseous-fibrous lesion. Undocumented radiographic changes and related bone metabolism disorder are herein hypothesized and discussed. We present an adolescent case with recurrent familial gigantiform cementoma who received surgical intervention in our hospital. Apart from typical multiquadrant and expansile ab...

acute leukemia is the most common malignancy in childhood, which mainly involves children less than 15 years of age. the growing skeleton is the main site of involvement in children. leukemic cells proliferate within the massive red bone marrow in children. so besides the pallor, petechia, purpura and ecchymosis in the skin and mucosal surfaces, bone pain and other bony lesions are other manife...

  Metastatic survey of the patients with known primary malignancies with bone scan is one of the most common studies in nuclear medicine. Unfortunately the conventional planar bone scan has a very low specificity for differentiating benign from malignant lesions especially in the spinal column. In this study, we compared the specificity of SPECT imaging and convention...

A 76-year-old man with symptomatic bone metastases from castrationresistant prostate cancer underwent Radium-223-dichloride (Ra-223) therapy. Before Ra-223 therapy, he had normal peripheral blood cell counts. Ra-223 therapy relieved his shoulder and low back pain. The elevation of the serum prostate-specific antigen (PSA), doubling every month during Ra-223 therapy, suggested a PSA flare or rel...

An 8-year-old, male neutered English Cocker Spaniel presented to the Royal Veterinary College for evaluation of reluctance to exercise and spinal hyperesthesia of 1-year duration. Medical treatment by referring veterinarian with antibiotics and tramadol did not result in clinical improvement. Survey radiographs performed before referral revealed multiple lytic bone lesions involving sternum and...

Abstract Subset of patients with H3G34 gliomas may present extra-CNS metastasis further complicating both diagnosis and treatment. We describe a case 19-year-old female presenting initially focal motor seizure in right leg along pain. MRI the showed an ill-defined distal femur expansile osteolytic lesion central fluid signal, thick rim enhancement, endosteal scalloping, cortical invasion, smoot...

BACKGROUND Aneurysmal bone cysts are relatively uncommon in the facial skeleton. These usually affect the mandible but origin from the coronoid process is even rarer. To the best of our knowledge, this is the first reported case of a coronoid process aneurysmal bone cyst presenting as temporal fossa swelling. CASE PRESENTATION A 17 year old boy presented with a progressively increasing swelli...