Export of macromolecules from the endoplasmic reticulum (ER) lumen into the cytosol is a major aspect of the quality control systems operating within the early secretory system. Glycopeptides are exported from the ER by an ATP- and GTP-dependent pathway, which shares many similarities to the protein export system. Significantly, for glycopeptides, there is no requirement for cytosolic factors, ...

The Bureau of Industry and Security (BIS) is amending the Export Administration Regulations (EAR) to reflect changes to the Missile Technology Control Regime (MTCR) Annex that were agreed to by MTCR member countries at the September and October 2014 Plenary in Oslo, Norway, and pursuant to the 2014 Technical Experts Meeting in Prague, Czech Republic. This rule also makes conforming changes to c...

Nucleo-cytoplasmic transport of proteins is mediated by nuclear export signals, identified in various proteins executing heterologous biological functions. However, the molecular mechanism underlying the orchestration of export is only poorly understood. Using microinjection of defined recombinant export substrates, we now demonstrate that leucine-rich nuclear export signals varied dramatically...

[1] The importance of biology to the ocean carbon sink is often quantified in terms of export, the removal of carbon from the ocean surface layer. Satellite images of sea surface chlorophyll indicate variability in biological production, but how these variations affect export and air-sea carbon fluxes is poorly understood. We investigate this in the North Atlantic using an ocean general circula...

In recent decades the weight of exports in economic activity has been increasing. Hence great importance is given to analysing the determinants of their behaviour. When such analysis is carried out, it often considers the determining variables to be only those that affect export demand, particularly competitiveness and external demand. Thus it does not take into account the factors that can inf...

Initiation of an immune response through expression of MHC class II and related genes is under the control of the CIITA. Normally found in both the cytoplasm and nucleus, CIITA is tightly controlled by a variety of posttranslational modifications as well as interactions with other nuclear and cytoplasmic factors, whereas disruption of this dual subcellular localization impairs CIITA functioning...

Eukaryotic tRNAs are synthesized in the nucleus and need to be exported to the cytoplasm where they function in translation. tRNA export is mediated by exportin-t, which binds tRNA directly and with high affinity. tRNAs are initially synthesized as precursor molecules. Maturation to functional tRNA takes place in the nucleus, precedes export, and includes trimming of the 5' and 3' ends, posttra...

Many bacteria move using a complex, self-assembling nanomachine, the bacterial flagellum. Biosynthesis of the flagellum depends on a flagellar-specific type III secretion system (T3SS), a protein export machine homologous to the export machinery of the virulence-associated injectisome. Six cytoplasmic (FliH/I/J/G/M/N) and seven integral-membrane proteins (FlhA/B FliF/O/P/Q/R) form the flagellar...

Using confidential firm-level data from the United States in 2002, we show that exporting firms charge prices for narrowly defined goods that differ substantially with the characteristics of firms and export markets. We control for selection into export markets using a three-stage estimator. We have three main results. First, we find that that highly productive and skillintensive firms charge h...

| More from the authors | Email niuxx@ eyou.com | Citation export 9. Pretreatment of petrochemical wastewater by coagulation and flocculation and the sludge characteristics. Verma S, Prasad B, Mishra IM: J Hazard Mater; 2010 Jun 15;178(1-3):1055-64 Abstract | More from the authors | Citation export 10. Evaluation of reusing alum sludge for the coagulation of industrial wastewater containing mix...