Red deer (Cervus elaphus) are hosts of liver fluke (Fasciola hepatica); yet, prevalence is rarely quantified in wild populations. Testing fresh samples from remote regions by faecal examination (FE) can be logistically challenging; hence, we appraise frozen storage and the use of a coproantigen ELISA (cELISA) for F. hepatica surveillance. We also present cELISA surveillance data for red deer fr...

Siendo la fasciolosis una infección parasitaria importante en rumiantes de muchos países y dada alta prevalencia humanos animales Cajamarca, Perú, se planteó realizar el estudio sobre perfil las proteínas intestino Fasciola hepatica con objetivo conocer número rango pH secreción/excreción del parásito que expresa mediante método electroforesis 2D-bidimensional. Las muestras adultas F. recolecta...

Circulating immune complexes were investigated by the 125I-Clq binding test in serum from patients with fascioliasis. Only 36% of all the patients studied showed significant levels of CIC. Nevertheless, when we considered only the patients eliminating Fasciola hepatica eggs in the stool and/or with the acute phase of the infection, the detection of CIC was very higher (more than 70% of the case...

During intraocular surgery of a 44-year-old woman from Guilan Province in north Iran, a small flat parasite was removed from the anterior chamber angle of the left eye. According to morphological characterisation of the parasite, it was identified as Fasciola hepatica. The route of entry of the parasite was not identified. Meanwhile, stool and serology examinations of the patient for diagnosis ...

background: we evaluated the genetic diversity of samples identified morphologically as fasciola spp. from sheep, cattle and goat from kermanshah province, western iran using pcr-rflp method. methods: we used pcr-rflp analysis of ribosomal its1 fragment using rsai restriction enzyme to investigate the genetic characteristics of fasciola species obtained from different hosts (16 sheep, 28 cattle,...

background: fascioliasis caused by fasciola hepatica and f. gigantica is a foodborne and waterborne zoonotic disease with a worldwide distribution. the illness occurs in regions with intensive sheep or cattle production. in some parts of iran the incidence of human infection has increased over the past decades. since chaharmahal and bakhtiyari province has been known as a main pole of tradition...

background: the trematodes of the genus fasciola (the liver flukes) are among the well-known instances of food-borne parasites worldwide. differentiation of fasciola species is important because of their different transmission and epidemio-logical characteristics. the current study was undertaken to discriminate fasciola species in the domestic ruminants of urmia city, iran. methods: adult fluk...

BACKGROUND Fasciola hepatica is not only responsible for major economic losses in livestock farming, but is also a major food-borne zoonotic agent, with 180 million people being at risk of infection worldwide. This parasite is sophisticated in manipulating the hosts' immune system to benefit its own survival. A better understanding of the mechanisms underpinning this immunomodulation is crucial...

To infect their mammalian hosts, Fasciola hepatica larvae must penetrate and traverse the intestinal wall of the duodenum, move through the peritoneum, and penetrate the liver. After migrating through and feeding on the liver, causing extensive tissue damage, the parasites move to their final niche in the bile ducts where they mature and produce eggs. Here we integrated a transcriptomics and pr...

BACKGROUND The nature of the immune response to infection is dependent on the type of infecting organism. Intracellular organisms such as Toxoplasma gondii stimulate a Th1-driven response associated with production of IL-12, IFN-gamma, nitric oxide and IgG2a antibodies and classical activation of macrophages. In contrast, extracellular helminths such as Fasciola hepatica induce Th2 responses ch...