Objective(s): The aim of present research was to develop matrix-mini-tablets of lornoxicam filled in capsule for targeting early morning peak symptoms of rheumatoid arthritis. Materials and Methods:Matrix-mini-tablets of lornoxicam were prepared by direct compression method using microsomal enzyme dependent and pH-sensitive polymers which were further filled into an empty HPMC capsule. To asses...

 The influence of five pure diets of isonitrogenous and isoenergic with different ratios of Clupeidae fish oil (F) and soybean oil (S) on growth, molting and survival of narrow-clawed crayfish, Astacus leptodactylus, was evaluated during an 8-weeks trial. As soybean oil replaced with fish oil in each treatment, gently. Test diets were inclusive F0/S100, F30/S70, F50/S50, F70/S30 and F100/S0 fis...

Introduction One of the most common mental disorders in elderly is depression. Because high frequency side effects pharmacotherapy and comorbid medical illnesses, there are not many ways to treat it. Non-drug therapies, such as repetitive transcranial magnetic stimulation (rTMS), could help overcome limitations standard drug therapy for this type disorders. Objectives Development approaches imp...

Aim This study aims to establish a nomogram model predict the relevance of SA in Chinese female patients with mood disorder (MD). Method The included 396 participants who were diagnosed MD Diagnostic Group (F30–F39) according 10th Edition Disease and Related Health Problems (ICD-10). Assessing differences demographic information clinical characteristics between two groups. LASSO Logistic Regres...

This paper constructs a two-country overlapping generations model with two distinct fiat monies in which seigniorage revenues are used to finance a local public good. Countries differ both in endowments and in the preference for the public good. Under perfect mobility of financial assets benevolent governments choose their rates of growth of money supply strategically and private individuals ha...

OBJECTIVE Extended release (XR) and immediate release (IR) quetiapine have differing dosing, titration and plasma concentration profiles. The authors assessed whether the use of quetiapine XR and IR in schizophrenia spectrum disorders (SCZ) and bipolar disorder (BD) differ. DESIGN Retrospective non-interventional registry study. SETTING Secondary healthcare. PARTICIPANTS All SCZ and BD (I...

Genetic and environmental factors are associated with psychosis risk, but the latter present more tangible markers for prevention. We conducted a theoretical exercise to estimate the proportion of psychotic illnesses that could be prevented if we could identify and remove all factors that lead to increased incidence associated with ethnic minority status and urbanicity. Measures of impact by po...

Low-grade inflammation is a risk factor for depression, psychosis and other major psychiatric disorders. It is associated with poor response to antidepressant and antipsychotics, and could potentially be a treatment target. However, there is limited data on the prevalence of low-grade inflammation in major psychiatric disorders, and on the characteristics of patients who show evidence of inflam...