BACKGROUND Patient reported outcomes (PROs) are especially useful in assessing treatments for rheumatoid arthritis (RA) since they measure dimensions of health-related quality of life that cannot be captured using strictly objective physiological measures. The aim of this study was to compare the effects of combination etanercept and methotrexate (ETN + MTX) versus combination synthetic disease...

ObjectivesIn our systematic review, we assessed past and current practice of patient-reported outcome (PRO) measurement in cancer randomized, controlled trials (RCTs).MethodsWe included RCTs with PRO endpoints evaluating conventional medical treatments, conducted patients the most prevalent solid tumor types (breast, lung, colorectal, prostate, bladder, gynecological cancers) either published 2...

Background Fatigue is one of the major complaints patients with rheumatoid arthritis (RA). However, literature relating fatigue to other disease-related parameters has presented discrepant results and longitudinal studies multivariate analyses are scarce. Objectives To explore potential associations between demographic variables patient-reported outcomes (PROMs) in RA treated biological disease...

Background: The efficacy and safety of baricitinib (BARI), an oral selective Janus kinase (JAK)1/JAK2 inhibitor, were evaluated in the randomized, controlled trial, RA-BEAM ( NCT01710358 ), patients (pts) with active rheumatoid arthritis (RA) inadequate responses (IR) to methotrexate (MTX). 1,2,3 Objectives: To compare time onset magnitude improvement across different patient-reported outcomes ...

Background Fatigue is a common constitutional feature and has significant impact on quality of life in patients with chronic inflammatory rheumatic diseases, such as psoriatic arthritis (PsA). It complex phenomenon its pathogenesis remains unclear. Despite being symptom, it largely ignored rarely assessed clinical practice. Objectives This study aims to evaluate the incidence severity fatigue P...

El Lupus Eritematoso Sistémico (LES) es una enfermedad autoinmune inflamatoria crónica que tiene como uno de sus síntomas más frecuentes la fatiga. La etiología ésta multifactorial, existen factores relacionados a propia enfermedad, estilos vida, comorbilidades y tratamiento están asociados. Asimismo, se cuenta con diversos para poder medirla, siendo los instrumentos utilizados: Escala Análoga ...