Since its introduction as a procedure of last resort in a terminally ill patient with intractable cancer-related pain, spinal cord stimulation has been used to effectively treat chronic pain of varied origins. Spinal cord stimulation is commonly used for control of pain secondary to failed back surgery syndrome and complex regional pain syndrome, as well as pain from angina pectoris, peripheral...

Abstract Excessive epidural fibrosis attached to the dura mater is major cause of recurrent failed back surgery syndrome after spine surgery. Neutrophil extracellular traps (NETs) promote fibrosis, raising possibility that DNA backbone NETs may be a potential target in therapy fibrosis. Human body temperature-sensitive hydroxypropyl chitin hydrogel solutions were prepared encapsulate DNase I, w...

Objectives.  The probability of success with spinal cord stimulation (SCS) depends largely on appropriate patient selection. Here, we have assessed the predictive value of pain etiology as it relates to pain relief with SCS as part of a prospective multicenter clinical trial. Methods.  Sixty-five subjects with chronic and intractable pain tested an epidural SCS system. Subjects reported pain ra...

conclusions the advantages of dsa in fluoroscopy-guided transforaminal epidural block and nerve block are identification of the degree of appropriate contrast flow (epidural and nerve root sleeve) and the intravascular administration without overlapping radiodense structures. introduction most pain physicians know that fluoroscopy might improve the safety, accuracy, and efficacy of nerve block;...

Background Insomnia frequently occurs to patients with persistent back pain. By worsening pain, mood, and physical functioning, insomnia could lead to the negative clinical consequences of patients with failed back surgery syndrome (FBSS). This retrospective and cross-sectional study aims to identify the risk factors associated with clinical insomnia in FBSS patients. Methods A total of 194 pat...

BACKGROUND The most common causes of failed back surgery are residual or recurrent herniation, foraminal fibrosis and foraminal stenosis that is ignored, untreated, or undertreated. Residual back ache may also be from facetal causes or denervation and scarring of the paraspinal muscles.(1-6) The original surgeon may advise his patient that nothing more can be done on the basis of his opinion th...

Background and Importance Lumbar pseudomeningocele is an extradural cystic collection of cerebrospinal fluid with no dural covering. It results from a breach in the dura–arachnoid layer. This rare complication results from a dural rent or dehiscence after laminectomy. The exact cause of postoperative pseudomeningocele incidence is unknown and is usually under reported, as most of these patients...