نتایج جستجو برای: fana fluorescent antinuclear antibodies
تعداد نتایج: 242796 فیلتر نتایج به سال:
OBJECTIVES To evaluate in patients with multiple sclerosis (MS) the occurrence of clinical systemic signs and biological autoimmune abnormalities, including positive titers of antinuclear antibodies and antiphospholipid antibodies, suggestive of autoimmune diseases that may affect the central nervous system. Also, to compare the clinical and magnetic resonance imaging features and evolution of ...
AND PRINCIPLES Autoimmune disorders can be Non-organ Specific, Tissue or Organ Specific or Overlapping assiciated with both organ specific and non organ specific antibodies. The five most common autoimmune antibodies include: 1. Antinuclear antibodies (ANA) 2. Antimitochondrial antibody (MA) 3. Antismooth muscle antibodies (SMA) 4. Antiparietal cell antibodies (PCA) 5. Antireticulin antibody (RA)
This is a review and update article on antinuclear antibodies assays, in particular the antinuclear factor, in which are approached histological and epidemiological aspects, physiopathogenesis, identification methods, their specificities and interpretation, correlating them to their applicability in the dermatologist's and general clinician's clinical practice.
Antinuclear antibodies (ANA) are primarily significant in the diagnosis of systemic connective tissue diseases. The relationship between their occurrence in allergic diseases is poorly documented. However, the mechanism of allergic and autoimmune diseases has a common thread. In both cases, an increased production of IgE antibodies and presence of ANA in selected disease entities is observed. E...
The incidence of patients with positive antinuclear antibody test results rose during three years of treatment with hydralazine. At the end of that period over half of the patients (both rapid and slow acetylators) had titres exceeding 1/20, but the rate of rise was faster in the slow acetylators than in the rapid. There was a significant relation between the cumulative dose of hydralazine and ...
BACKGROUND Although much is known about the natural history of systemic lupus erythematosus (SLE), the development of SLE autoantibodies before the diagnosis of the disease has not been extensively explored. We investigated the onset and progression of autoantibody development before the clinical diagnosis. METHODS The Department of Defense Serum Repository contains approximately 30 million s...
BACKGROUND Neonatal lupus erythematosus (NLE) is a transient autoimmune disease of developing fetus and neonate in mothers with systemic lupus erythematosus (SLE). In this report we introduce an infant with NLE whose mother had rheumatoid arthritis. CASE PRESENTATION Our case was a 40 day old male infant with discoid-like and annular skin lesions over forehead and neck, irritability and low g...
Antinuclear antibodies are a hallmark feature of generalized autoimmune diseases, including systemic lupus erythematosus and systemic sclerosis. However, the processes underlying the loss of tolerance against nuclear self-constituents remain largely unresolved. Using mice deficient in lymphotoxin and Hox11, we report that approximately 25% of mice lacking secondary lymphoid organs spontaneously...
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