نتایج جستجو برای: fasting glucose

تعداد نتایج: 200145  

2011
Xiaolin Luo Yongxian Zhang Xiangbo Ruan Xiaomeng Jiang Lu Zhu Xiao Wang Qiurong Ding Weizhong Liu Yi Pan Zhenzhen Wang Yan Chen

OBJECTIVE Most animals experience fasting-feeding cycles throughout their lives. It is well known that the liver plays a central role in regulating glycogen metabolism. However, how hepatic glycogenesis is coordinated with the fasting-feeding cycle to control postprandial glucose homeostasis remains largely unknown. This study determines the molecular mechanism underlying the coupling of hepati...

Journal: :The Journal of clinical investigation 2008
Wei-Min Chen Michael R Erdos Anne U Jackson Richa Saxena Serena Sanna Kristi D Silver Nicholas J Timpson Torben Hansen Marco Orrù Maria Grazia Piras Lori L Bonnycastle Cristen J Willer Valeriya Lyssenko Haiqing Shen Johanna Kuusisto Shah Ebrahim Natascia Sestu William L Duren Maria Cristina Spada Heather M Stringham Laura J Scott Nazario Olla Amy J Swift Samer Najjar Braxton D Mitchell Debbie A Lawlor George Davey Smith Yoav Ben-Shlomo Gitte Andersen Knut Borch-Johnsen Torben Jørgensen Jouko Saramies Timo T Valle Thomas A Buchanan Alan R Shuldiner Edward Lakatta Richard N Bergman Manuela Uda Jaakko Tuomilehto Oluf Pedersen Antonio Cao Leif Groop Karen L Mohlke Markku Laakso David Schlessinger Francis S Collins David Altshuler Gonçalo R Abecasis Michael Boehnke Angelo Scuteri Richard M Watanabe

Identifying the genetic variants that regulate fasting glucose concentrations may further our understanding of the pathogenesis of diabetes. We therefore investigated the association of fasting glucose levels with SNPs in 2 genome-wide scans including a total of 5,088 nondiabetic individuals from Finland and Sardinia. We found a significant association between the SNP rs563694 and fasting gluco...

2016
Sunjai Gupta Robert Anderson Richard IG Holt

BACKGROUND Depression and bipolar illness are associated with a 2-3 fold increase in the prevalence of diabetes. However, it is unknown whether variation in mood affects glucose metabolism. The aim of this study was to assess whether changes in affect were related to fasting plasma glucose and glycated haemoglobin. METHODS 379 men and 441 women who took part in the 2003 Health Survey for Engl...

Fatemeh Nikseresht, Masoud Rahmati, Mostafa Bahrami,

Objective: Hepatic glucose release plays a potential role in hyperglycemia in type 2 diabetes (T2D) patients. The aim of this experimental study was to determine the effect of 6 weeks of high-intensity interval training (HIIT) on fasting levels of glucose and insulin as well as glucokinase (GCK) expression in liver tissue in obese T2D rats. Materials and Methods: T2D was induced by a high-fat ...

2011
Laura J. Rasmussen-Torvik Man Li Wen H. Kao David Couper Eric Boerwinkle Suzette J. Bielinski Aaron R. Folsom James S. Pankow

OBJECTIVE Elevated fasting glucose level is associated with increased carotid intima-media thickness (IMT), a measure of subclinical atherosclerosis. It is unclear if this association is causal. Using the principle of Mendelian randomization, we sought to explore the causal association between circulating glucose and IMT by examining the association of a genetic risk score with IMT. RESEARCH ...

Journal: :BMC Public Health 2007
Cai Le Virasakdi Chongsuvivatwong Alan Geater

BACKGROUND We examined independent influences of contextual variables on cardiovascular risk factors in Shilin county, Yunnan province, South-west China. METHODS Three villages were selected from each of the ten townships based on probability proportional to size. In each selected village, 200 individuals aged > or = 45 years were chosen based on simple random sampling method. From 6006 indiv...

Journal: :Clinical chemistry 2003
Mark A Pereira David S Ludwig

Recent case-series studies and smaller cross-sectional samples have reported alarming observations among youth: once a disease of middle age and older adulthood, type 2 diabetes now represents nearly one-half of newly diagnosed diabetes cases in some obese adolescent African-American and Hispanic populations (1 ). Furthermore, the metabolic syndrome, also known as syndrome X or the insulin resi...

Bagher Moradi, Fateme Tashrifi, Mehdi Abdollahi, Ozra Haghani Nasimi,

Objective: Gestational diabetes mellitus (GDM) is the most common metabolic disorder during pregnancy. This study aimed to compare the prevalence of GDM positive screening tests with Fasting Blood Sugar (FBS) and Glucose Challenge Test (GCT) in pregnant women without risk factors in Esfarayn, Iran. Materials and Methods: This descriptive study was conducted on 997 pregnant women, who were refe...

Journal: :Diabetes care 2005
Marc J Weigensberg Geoff D C Ball Gabriel Q Shaibi Martha L Cruz Michael I Goran

OBJECTIVE To determine whether overweight Latino children with impaired fasting glucose (IFG) (> or = 100 mg/dl) have increased insulin resistance or decreased beta-cell function compared with those with normal fasting glucose (NFG). RESEARCH DESIGN AND METHODS We studied 207 healthy overweight Latino children, aged 8-13 years, with a family history of type 2 diabetes. Fasting and 2-h glucose...

Journal: :فصلنامه علمی پژوهشی گیاهان دارویی 0
h fallah huseini 1- pharmacology & applied medicine department of medicinal plants research center, institute of medicinal plants, acecr s mehrzadi 1- pharmacology & applied medicine department of medicinal plants research center, institute of medicinal plants, acecr h ghaznavi 2- department of pharmacology, school of medicine, iran university of medical sciences y tajallizadehkhoob 4- endocrinology & metabolism research institute, tehran university of medical sciences h fakhrzadeh endocrinology and metabolism research institute, tehran university of medical sciences, 5th floor, dr shareeati hospital, north karegar avenue, tehran, iran tel: +98-21-84902476-7, fax: +98-21-88220052

background: diabetes mellitus type 2 with dyslipidemia is a common disease. previous studies suggest that chemical constituent present in pinus eldarica (p. eldarica) nut posesess antioxidant properties and positively affect glucose metabolism. however blood glucose and cholesterol lowering effects of p. eldarica nut have not been studied so far. objective: the present study was undertaken to e...

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