BACKGROUND Narcolepsy is a severe sleep-wake cycle disorder resulting in most cases from a lack of orexin, the energy balance-regulating hormone. Narcoleptic patients have been reported to suffer from an excess morbidity of Type 2 diabetes, even after correction for their often elevated body mass index. METHODS To explore whether narcolepsy is specifically associated with a propensity to deve...

abstract objective: insulin resistance and hyperinsulinemia are common among the women with polycystic ovarian syndrome (pcos). familial aggregation of pcos has implications on the role of heredity in this disease. the aim of this study was to evaluate insulin resistance among the fathers, mothers, and siblings of the women with pcos referring to the clinics affiliated to shiraz university of m...

BACKGROUND & OBJECTIVES Recent data suggest that insulin resistance can predict cardiovascular disease independently of the other risk factors, such as hypertension, visceral obesity or dyslipidaemia. However, the majority of available methods to evaluate insulin resistance are complicated to operate, expensive, and time consuming. This study was undertaken to assess whether serum lipoprotein r...

background: in 2-4% of couples in fertile ages, recurrent pregnancy loss (rpl) occurs which consisted one out of 300 pregnancies. the aim of this study was to comparison insulin resistance (ir) in patients with rpl to normal individuals. materials and methods: in a case-controlled, prospective study, 49 non-pregnant, non-diabetic women with early rpl as the case group and 49 non-pregnant, non-d...

hyperglycemia and gestational diabetes mellitus are complications of pregnancy. both mothers and newborns are typically at increased risk for complications. this study sought to determine effect of zinc supplementation on serum glucose levels, insulin resistance, energy and macronutrients intakes in pregnant women with impaired glucose tolerance.in this clinical trial 44 pregnant women with imp...

OBJECTIVES To evaluate fasting serum insulin levels and insulin resistance, and their association with blood rheology, in Japanese young adults without diabetes. METHODS Blood samples were analysed and blood rheology was estimated using haematological parameters. Whole blood passage time was measured using a Hitachi MC-FAN(©) microchannel array flow analyser. RESULTS Out of 151 subjects (me...

BACKGROUND & OBJECTIVES Elevated levels of c-reactive protein (CRP) are known to be associated with insulin resistance and metabolic syndrome in adults. A substantial prevalence of hyperinsulinaemia and elevated CRP levels have been shown in Indian young adults. We therefore studied the association of serum high-sensitivity C-reactive protein (hs-CRP) with fasting insulin and insulin resistance...

conclusions based on these data, we can argue that circulating glucose concentration is not directly affected by serum resistin in t2dm. it seems that resistin affects glucose indirectly, through insulin resistance. results we found that serum resistin had a positive significant correlation with insulin resistance (p = 0.000, r = 0.64). no significant correlation was found between serum resisti...

Abstract Objective: Insulin resistance and hyperinsulinemia are common among the women with polycystic ovarian syndrome (PCOS). Familial aggregation of PCOS has implications on the role of heredity in this disease. The aim of this study was to evaluate insulin resistance among the fathers, mothers, and siblings of the women with PCOS referring to the clinics affiliated to Shiraz University of ...