We investigated whether β-adrenergic antagonists attenuates dietary fat absorption through the regulation of pancreatic lipase (PNLIP) expression in pancreatic acinar cells in the context of high fat diet feeding. Male six-week-old C57BL/6 mice were assigned into an ad libitum fed control diet (CON) and a high fat diet (HIGH). Within each diet group, subgroups of mice were treated with vehicle ...

An electron microscopic study of the morphology of fat absorption in the duodenum of normal and fat-fed mice supports the view that all absorbed fat passes through the cytoplasm of absorptive cells. The Golgi complex plays an important role in the transport of fat across these cells.

Bile salts function to emulsify lipids and fat solubles to form fat-containing micelles to ease absorption from the intestinal tract. However, in animals, including humans, the production and utilization of bile salts is very limited at birth and during early development stages. In humans, insufficient bile has been associated with lipid malabsorption in premature infants (Watkins et al., 1975)...

Reasons were given in 1948 (Sheldon) for thinking that in coeliac children starch intolerance might be of greater etiological significance than a failure to absorb the products of fat digestion. In a later communication (Sheldon, 1949), from a study of fat balances in a group of fifteen children with coeliac disease, it was concluded that withdrawal of starch from the diet was accompanied by a ...

The various gross symptoms of essential fatty acid deficiency in the rat are well recognized, but little is known about the metabolic features of this disease. The purpose of this investigation was to study the influence of fat deficiency on the rate of absorption and transport of fat through the intestinal mucosa. The scheme of fat labeling by the use of spectroscopically active methyl esters ...

The presence on carbon-3 of a free hydroxyl group that may be esterified is a common characteristic of the known sterol inhibitors of cholesterol absorption. The 30-carbon stcrols found in wool fat possess such a group, but differ from the previously demonstrated inhibitors of cholesterol absorption in that they do not form insoluble precipitates with digitonin. To determine whether these subst...

Background: The objective of this study was to determine the proximate compositions and sensory characteristics as well functional properties flour blends cookies made from wheat, soybean rice bran in ratios (M1) 100:0:0, (M2) 90:6:4, (M3) 80:12:8, (M4) 70:17:13 (M5) 40:35:25%. Methods: were prepared using Okpala et al. (2013) method with slight changes. Moisture, protein, fat, fiber carbohydra...

Vitamin A acetate and vitamin A alcohol, triolein I(131), oleic acid I(131), and fat balance tests have been assessed in studies on cases of coeliac disease, pancreatic insufficiency, and some disorders of the small intestinal wall. In coeliac disease a very low serum carotene and flat vitamin A absorption curves have been noted. The contrast between vitamin A acetate and alcohol curves has bee...

The molecular structure of the four fat-soluble vitamins and of cholesterol, the major intestinal sterol in man, are shown in Figure 1. In spite of the obvious dissimilarities that exist between these compounds they possess one common feature, namely, they are all nonpolar lipids with extremely low solubilities in aqueous media. Because of this, it is convenient to consider them together when e...