INTRODUCTION: Pedal fat pad atrophy is associated with pain, decreased tissue thickness, and elevated foot pressures. To date, no objective studies have investigated the utility of injecting fat into the forefoot to treat this costly and debilitating form of lipoatrophy. We hypothesize that pedal fat grafting can reduce pain, improve function, increase tissue thickness, and decrease pedal press...

Common variants of human fat mass- and obesity-associated gene Fto have been linked with higher body mass index, but the biological explanation for the link has remained obscure. Recent findings suggest that these variants affect the homeobox protein IRX3. Here we report that FTO has a role in white adipose tissue which modifies its response to high-fat feeding. Wild type and Fto-deficient mice...

The excess weight of obese people is not all attributable to fat. Adipose tissue contains cells with their nuclei, blood vessels and nerves in addition to fat. In most obese people there may be hypertrophy of skeletal and cardiac muscle, and perhaps of other organs, which have to support and move the increased mass of fat. Keys & Broiek (1953) introduced the term 'obesity tissue' to describe th...

Isolation of total RNA from frozen muscle and fat samples typically results in small yields due to the presence of connective tissue between muscle fibers, which impairs complete tissue homogenization, and the excess of fat and relatively small cellularity of adipose tissue. Meat quality studies involve determination of fatty acid composition and content from muscle and subcutaneous fat samples...

Different visceral fat compartments have several systemic effects and may play a role in the development of both insulin resistance and cardiovascular diseases. In the last couple of years special attention has been paid to the epicardial adipose tissue (EAT), which can be quantified by non-invasive cardiac imaging techniques. The epicardial fat is a unique fat compartment between the myocardiu...

Background: The high saturated fatty acid content of beef has been linked to obesity and cardiovascular diseases. study investigated the impact black seed oil (BSO) on fat-altered hemato-biochemical pathophysiological alterations in albino mice. Methods: Twenty four Swiss Albino mice (Mus musculus) 25-28 days old were equally divided into three groups (n=8) namely A, B C. Mice group A was desig...

a 75-year-old woman presented with six months history of progressing lagophthalmos and immobility of the left eye. magnetic resonance imaging (mri) of the orbit demonstrated infiltration of orbital fat and the extra-ocular muscles. we performed transverse blepharotomy of the left eyelid to correct lagophthalmos; and during surgery, we took a biopsy sample from levator muscle and orbital fat. af...

Tissue engineering technologies are new and promising techniques in fat tissue reconstruction. However, to assess their efficacy before any clinical application, in vivo experiments are mandatory. This study assesses whether microcomputed tomography (CT) scan imaging is suitable to analyze in vivo the behavior of injected engineered polymer and changes in fat tissue. The volume of mice inguinal...