STUDY OBJECTIVE To study the diagnostic role of flexible bronchoscopy (FB) in immunocompromised patients with pulmonary infiltrates. DESIGN Prospective, observational study. SETTING Tertiary care hospital. PATIENTS A total of 104 consecutive non-HIV-infected immunocompromised patients with lung infiltrates in whom FB was performed. METHODS The primary outcome measure was the diagnostic ...

The hybrid modular multilevel converter (HMMC) composed of half-bridge (HB) and full-bridge (FB) submodules (SMs) is an alternative to the FB-modular (MMC) with lower loss cost. However, HMMC's maximum reverse-biased voltage (RBV) than FB-MMC, so does dc fault clearing capability (DCFCC). Reduced RBV will prolong time, especially when side inductance large. In this letter, auxiliary circuit pro...

Most respondents state that Flow Based market coupling (FB) optimizes the allocation of cross-border capacity, which entails higher social welfare and higher price convergence. Better cooperation between TSOs is also mentioned, since FB forces TSOs and Exchanges to work together. According to most respondents FB will also lead to better transparency regarding critical branches and shadow prices...

We analyze the impact of size-based scheduling on the flow level performance of elastic traffic in wireless downlink data channels. The impact is assessed by comparing the flow level delay of the simple RR scheduler to two optimized non-anticipating schedulers (FB and FB◦) and SRPT. The optimized distance-aware scheduler FB◦ is derived by applying the Gittins index approach. Our results show th...

We compare the overall mean response time (a.k.a. sojourn time) of the processor sharing (PS) and feedback (FB) queues under an M/GI/1 system. We show that FB outperforms PS under service distributions having decreasing failure rates; whereas PS outperforms FB under service distributions having increasing failure rates. c © 2003 Elsevier B.V. All rights reserved.

Interleukin-2 (IL2) is a cytokine that can stimulate cytotoxic immune cells to attack infected and malignant cells. Unfortunately, IL2 can also cause serious immune-related toxicity. Recently, a mutant of IL2 (IL2v) with abolished CD25 binding, increased plasma half-life and less toxicity was engineered. Unlike wild-type IL2 (wt-IL2), mutant IL2v does not bind to the α-subunit (CD25) of the hig...