Total hip replacement in patients with advanced osteonecrosis of the femoral head is often complicated by early loosening of the femoral component. Recent evidence has suggested that abnormal bone extending into the proximal femur may be responsible for the early failure of the femoral component. We aimed to identify which patients were at high risk of early failure by evaluating gadolinium-enh...

a 64-year-old woman, with amyloid related kidney failure (on renal dialysis) had a bone scan because of pain in the right upper femur. the 99m tc-mdp images revealed marked hepatic uptake. in addition, there was right proximal femoral concentration of radiotracer, which corresponded to a fracture site. as an added finding, the same femor demonstrated circumferential uptake at the lower pole. th...

PURPOSE We aimed to test our primary hypothesis that the effects of methylprednisolone on bone marrow in chickens are age-sensitive and increase with prolonged treatment and our secondary hypothesis that the effects of methylprednisolone on bone marrow can have individual effects. METHODS Sixteen control (group A) and 29 methylprednisolone-treated (group B) chickens were categorised by age: p...

It is unclear if a decrease in cancellous bone density or cortical bone thickness is related to sacral insufficiency fractures. We hypothesized that reduction in overall bone density leads to local reductions in bone density and cortical thickness in cadaveric sacra that match clinically observed fracture patterns in patients with sacral insufficiency fractures. We used quantitative computed to...

CONTEXT Serum 25-hydroxyvitamin D (25OHD) concentrations greater than 30 ng/ml have been recommended for lowering fracture risk. OBJECTIVE Our objective was to determine whether 25OHD sufficiency is a prerequisite for effective response to teriparatide (TPTD). DESIGN AND PATIENTS Data were from 1620 osteoporotic postmenopausal women in the Fracture Prevention Trial. The response to TPTD was...

BACKGROUND Hip fracture is associated with pronounced morbidity and excess mortality in elderly women with postmenopausal osteoporosis. Many drugs have been developed to treat osteoporosis and to reduce the risk of osteoporotic fractures. We investigated the effects of combined alendronate and vitamin D3 treatment on bone mass and fracture load at the femoral neck in ovariectomized (OVX) rats, ...

A clinical example is presented that demonstrates the capabilities of magnetic resonance imaging (MRI) in diagnosis a subchondral insufficiency fracture medial femoral condyle. An MR study protocol has been demonstrated allows ensure successful this type fracture.

BACKGROUND In this article, we aimed to discuss treatment strategies in fracture of the femoral head, which is a very rare injury. METHODS We reviewed five patients (six fractures) who admitted to our emergency department due to femoral head fracture between March 2006 and December 2007. Functional outcomes of the patients who were treated operatively and nonoperatively were compared. RESUL...

This paper reviews the management and progress of sixty-five cases of high fracture of the femoral neck treated by excision of the head and replacement b an acrylic head prosthesis. The behaviour of the reconstructed hip joints has been studied during the second, third, and, in a few cases, the fourth years after operation, and found to follow a definite general j);1tt r1L \‘ar\-ing slightly wi...

Antibiotic cement-coated intramedullary nails maintain a locally high antibiotic concentration while contributing to bone stability. We present a case of femoral subtrochanteric fracture in a patient with an infected nonunion who was successfully treated for an infection and nonunion using an antibiotic cement-coated tibial intramedullary nail. A 79-year-old woman with a right femoral subtrocha...