Altered lipid metabolism has been shown in fish fed plant protein sources. The present study aimed to gain further insights into how intestinal and hepatic lipid absorption and metabolism are modulated by plant meal (PM) and soya-saponin (SA) inclusion in salmon feed. Post-smolt Atlantic salmon were fed for 10 weeks one of four diets based on fishmeal or PM, with or without 10 g/kg SA. PM inclu...

BACKGROUND Hypercholesterolemia is an important risk factor for the development of coronary artery disease. Some dietary polyphenols, such as coffee polyphenols (CPPs), reduce cholesterol levels. The mechanism of this cholesterol-lowering effect is not fully understood, although 5-CQA, a major component of CPPs, reportedly inhibits cholesterol biosynthesis. Here, we investigated the mechanism o...

The prevalence of short bowel syndrome appears to be increasing because of more aggressive surgical and medical approaches to the management of neonatal intraabdominal catastrophies. Hence, a large cohort of neonates with intestinal failure occupies neonatal intensive care units, requiring chronic total parenteral nutrition (TPN) in hopes that the residual bowel will adapt, thereby permitting w...

The Mekong region presents a record incidence of cholangiocarcinoma (bile duct cancer). Scientists identify correlations between the development this aggressive disease and consumption raw fish in local dishes. While made aware these by comprehensive health campaigns, some villagers Thailand’s notoriously neglected Northeast refuse to cook before consumption: phenomenon that puzzles medical exp...

Dietary absorption of lipophilic contaminants may be a significant route of exposure in aquatic organisms. Bile salts, lipids, and humic acids are important factors that may influence the intestinal absorption of a contaminant such as benzo[a]pyrene (BaP). We hypothesized that bile salts, monoglycerides, and free fatty acids would increase BaP intestinal absorption, while triglycerides, humic a...

Petroleum refinery wastes contain mixtures of toxic compounds including Polycyclic Aromatic Hydrocarbons (PAH) which may pose genotoxic threats to the biota. The objective present study was assess potential wastewaters petroleum at Sapugaskanda, Sri Lanka using erythrocytic micronuclei and nuclear abnormalities as biomarkers in fish Oreochromis niloticus exposed wastewater under controlled labo...

This study was conducted to evaluate juveniles' Ocyurus chrysurus (13.7 ± 0.45 g initial weight) utilize lipid as an energy source on growth, feed efficiency, body composition, digestive and hepatic enzyme activities. Four diets of two protein levels (40 50%) with (6 12%) 2% digestible carbohydrates were formulated. Fish fed for 60 days apparent satiation at a stocking density 10 fish per tank ...