The structure-activity relationships between flavonoids and their tracheal relaxant action are little known. In the present study, 26 natural and synthetic flavonoids, divided into the five classes of flavones, flavonols, flavanones, isoflavones, and chalcones, were tested, and their IC (50) values were determined. The IC (50) values of these five classes indicated that flavones were more poten...

When processing citrus fruits into concentrated juice, enterprises generate waste in the form of peel, pit, and pulp. These wastes, especially are rich useful biologically active substances. The most representative terms content valuable from point view use medicine food industry, groups substances flavonoids carbohydrates. Flavanones known for their multifunctional antioxidant action. dominant...

Hop (Humulus lupulus L.) is a clonally propagated, dioecious, perennial, climbing plant used commercially for their secondary metabolites. The resins containing α- and β-acids, essential oils produced by the lupulin glands, present on female flowers are to add bitterness, aroma flavour beer. Recently, flavonoids, including chalcones flavanones, of hops have been shown exert variety biological a...

A few flavanones were synthesised by cyclisation of corresponding 3-(heteroaryl)-1(2-hydroxyphenyl) prop-2-en-1-one with sodium acetate in alcohol-water and evaluated for activity. Synthesised compounds were assayed for their in vitro anticancer activity against three human cancer cell lines, mammary adenocarcinoma (MCF7), human colon adenocarcinoma (HT29) and human kidney adenocarcinoma (A498)...

Flavanone was synthesized through the Claisen–Schmidt condensation between benzaldehyde and acetophenone and subsequent intramolecular Michael addition over aminopropyl-functionalized SBA-15 materials. The catalysts with well-ordered hexagonally arranged mesopores were synthesized by one-pot co-condensation of tetraethoxysilane and aminopropyltriethoxysilane using amphiphilic block copolymer as...

With growing concerns over multidrug resistance microorganisms, particularly strains of bacteria and fungi, evolving to become resistant to the antimicrobial agents used against them, the identification of new molecular targets becomes paramount for novel treatment options. Recently, the use of new treatments containing multiple active ingredients has been shown to increase the effectiveness of...