Oral controlled release systems are designed to release the drug in-vivo with prediction so as to increase efficacy, minimize adverse effects and increase bioavailability of drugs. Floating drug delivery systems (FDDSs) are expected to remain buoyant in a lasting way upon the gastric contents. The various buoyant preparations include hollow microspheres, granules, powders, tablets, capsules, pi...

The error-ranges of exact rational numbers and intervals can be guaranteed even during the arithmetic operations whereas we cannot rely on the error-ranges of floating-point numbers. In this paper, we propose a novel number system, where the exact rational numbers are strictly separated from inexact floating point numbers and carefully integrated with the inexact numbers. A three-valued logic i...

A biphasic gastroretentive drug delivery system of fenoverine was developed to maintain constant plasma concentration. The delivery system consisted of a loading-dose tablet and a floating multiple matrix tablet prepared by the direct compression process. The drug release from biphasic GRDDS in 0.1 mol L(-1) HCl and SGF (enzyme free) was sustained over 12 h with buoyant properties. Stability st...

In the present study, Floating Drug Delivery Beads (FDDS) were prepared with sodium alginate/ starch blend as a matrix, sodium hydrogen carbonate as a pore forming agent, methyl cellulose as a binder and barium chloride solution as a hardening agent. In order to prepare the beads with different porosity and morphology the ratio between pore forming agent to polymer blend and ratio of the co...

Numerical linear algebra algorithms use the inherent elegance of matrix formulations and are usually implemented using C/C++ floating point representation. The system implementation is faced with practical constraints because these algorithms usually need to run in real time on fixed point digital signal processors (DSPs) to reduce total hardware costs. Converting the simulation model to fixed ...

In the recent high speed processor, floating point ALU (FP ALU) is one of the important units to perform the arithmetic and logical functions of the floating point number. Floating point multiplication is one of the arithmetic operations that take more computational time and when implemented in hardware, it requires more area due to the large number of component. However the advantage of implem...

The present paper deals with the development of a multi-purpose floating tension leg platform (TLP) concept suitable for combined offshore wind and wave energy resources exploitation, taking into account prevailing environmental conditions at selected locations along European coastline. examined Renewable Energy Multi-Purpose Floating Offshore System (REFOS) encompasses an array hydrodynamicall...