An innovative vacuum capillary pneumatic actuation concept that can be used for point-of-care testing has been investigated. The vacuum glass capillaries are encapsulated within a laminated pouch and incorporated into the fluidic card. Vacuum glass capillaries broken by external force such as finger pressure, generate the pneumatic forces to induce liquid flow in the fluidic system. The sizes o...

The present work establishes the optimized spatial arrangement for an array of aligned microcantilever sensors placed inside a fluidic cell. The results of the present investigation show that the optimum spacing distance between the microcantilevers decreases as the fluidic cell height decreases. An increase in the flow Reynolds number is found to increase the optimum spacing distance. However,...

We report a method for making ultra-thin PDMS membrane devices. Freely suspended membranes as thin as 70 nm have been fabricated. Bulging tests were performed with a custom built fluidic cell to characterize large circular membranes. The fluidic cell allows the media (such as air or water) to wet one side of the membrane while maintaining the other side dry. Pressure was applied to the membrane...

This paper reports the design of a new type of micro-fabricated device allowing the directed axon outgrowth from different neuronal subtypes and their subsequent connections to create live neural networks. Micro-fluidic cell culture systems enable the fluidic isolation of the neuronal cell bodies from their axons. Our novel chamber design enables directed axon outgrowth between different neuron...

We have integrated electronic, optical, magnetic, thermal and fluidic devices into systems to construct useful analysis tools. Over the past several years, we have developed soft lithography approaches to define microfluidic systems in which pico-Liter volumes can be manipulated. These fluidic delivery systems have more recently been integrated with optical and electronic devices. We have also ...

This paper describes electrically-activated fluidic valves that operate based on electrowetting through textiles. The valves are fabricated from electrically conductive, insulated, hydrophobic textiles, but the concept can be extended to other porous materials. When the valve is closed, the liquid cannot pass through the hydrophobic textile. Upon application of a potential (in the range of 100-...

The application of electrical fields within a microfluidic channel enables many forms of manipulation necessary for lab-on-a-chip devices. Patterning electrodes inside the microfluidic channel generally requires multi-step optical lithography. Here, we utilize an ion-implantation process to pattern 3D electrodes within a fluidic channel made of polydimethylsiloxane (PDMS). Electrode structuring...

We present a novel 3D printed multimaterial microfluidic proportional valve. The microfluidic valve is a fundamental primitive that enables the development of programmable, automated devices for controlling fluids in a precise manner. We discuss valve characterization results, as well as exploratory design variations in channel width, membrane thickness, and membrane stiffness. Compared to prev...

This research proposes a substrate-integrated waveguide (SIW) cavity sensor to detect several chemicals using the microwave frequency range. The frequency response of the presented SIW sensor is switched by filling a very small quantity of chemical inside of the fluidic channel, which also causes a difference in the effective permittivity. The fluidic channel on this structure is either empty o...

As a system using a conventional unidirectional air turbine in oscillating water column (OWC) based on a wave energy plant, a twin unidirectional impulse turbine topology has been suggested in previous studies. However, the average efficiency of the suggested twin turbine is considerably lower than that of a conventional unidirectional turbine in this topology because reciprocating air flow can...