نتایج جستجو برای: fluoro β diketones

تعداد نتایج: 185255  

Journal: :Journal of medicinal chemistry 2010
Michael J Sofia Donghui Bao Wonsuk Chang Jinfa Du Dhanapalan Nagarathnam Suguna Rachakonda P Ganapati Reddy Bruce S Ross Peiyuan Wang Hai-Ren Zhang Shalini Bansal Christine Espiritu Meg Keilman Angela M Lam Holly M Micolochick Steuer Congrong Niu Michael J Otto Phillip A Furman

Hepatitis C virus (HCV) is a global health problem requiring novel approaches for effective treatment of this disease. The HCV NS5B polymerase has been demonstrated to be a viable target for the development of HCV therapies. β-d-2'-Deoxy-2'-α-fluoro-2'-β-C-methyl nucleosides are selective inhibitors of the HCV NS5B polymerase and have demonstrated potent activity in the clinic. Phosphoramidate ...

Journal: :nanochemistry research 1999
mostafa karimkoshteh marziyeh bagheri behzad zeynizadeha

various aldoximes and ketoximes synthesis of corresponding aldehydes and ketones in the presence of sio2@feso4 nano composite as recoverable nano catalyst and nh2oh·hcl. the sio2@feso4 nano composite system was carried out between 10 to 15 min in oil bath (70-80 °c) under solvent-free condition in excellent yields in addition this protocol can be used for industrial scales. this method offers s...

2011
M. A. FAROOQUE M. R. ISLAM G. T. RAHMAN

Ferrocenyl-β-diketone ligands have been synthesised by the reaction of (ferrocenyl methyl) trimethyl ammonium iodide (FcCH2N Me3I ), where Fc=C5H5FeC5H4 – with sodium salt of -β-diketone [Na+CH-(COR1) (COR2), where R1= R2=CH 3, R1= CH 3 , R2=Ph, R1= R2=CMe 3 ]. The formula of the ligands (1-3) are FcCH 2 CH(COCH 3 )(COCH 3 ), FcCH 2 CH(COCH 3 )(COPh) and FcCH 2 CH(COCMe 3 ) 2 respectively. The ...

Journal: :Acta Crystallographica Section C Crystal Structure Communications 2010

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