نتایج جستجو برای: follicular dendritic cell sarcoma

تعداد نتایج: 1769168  

2015
Zoran Gatalica Nurija Bilalovic Juan P. Palazzo Ryan P. Bender Jeffrey Swensen Sherri Z. Millis Semir Vranic Daniel Von Hoff Robert J. Arceci

The histiocytoses are rare tumors characterized by the primary accumulation and tissue infiltration of histiocytes and dendritic cells. Identification of the activating BRAFV600E mutation in Erdheim-Chester disease (ECD) and Langerhans cell histiocytosis (LCH) cases provided the basis for the treatment with BRAF and/or MEK inhibitors, but additional treatment options are needed. Twenty-four cas...

Journal: :International journal of clinical and experimental pathology 2008
Qingmei Xie Lugen Chen Kai Fu Josephine Harter Ken H Young Jaya Sunkara Deborah Novak Esperanza Villanueva-Siles Howard Ratech

The diagnosis of follicular dendritic cell (FDC) sarcoma can be challenging because of its morphologic overlaps with many other spindle cell neoplasms and, therefore, new phenotypic markers will be helpful in its differential diagnosis. Podoplanin is a mucin-type transmembrane glycoprotein that has recently been detected in reactive FDCs. In this study, we investigated the expression patterns o...

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2019

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