The human AmphyphisinII/Bin1 N-BAR domain belongs to the BAR domain superfamily, whose members sense and generate membrane curvatures. The N-BAR domain is a 57 kDa homodimeric protein comprising a six helix bundle. Here we report the protein folding mechanism of this protein as a representative of this protein superfamily. The concentration dependent thermodynamic stability was studied by urea ...

This document describes the design and construction of a mechanical device that allows subject with ectrodactyly to perform power grip. For this purpose, coupled bar mechanism for emulation finger is presented, system allows, from single movement, large diameter grip, considering variables obtained anthropometric goniometric measurement techniques. complemented by kinematic static analysis, in ...

In this paper, a novel unsymmetrical five–four bar Planar Parallel Manipulator (PPM) with three Degree-of-Freedoms (DOFs) is proposed, the new manipulator is composed of a double-layer five-bar part with a four-bar part located in between. Targeting for the application of Chinese dish cooking machine, the detailed kinematics analysis for the new PPM is developed. Different from traditional thre...

At present, multi-bar linkage mechanism is one of the most important directions of mechanical presses’ development. Utilizing the typical multi-linkage drawing mechanism of the plunger slide and compounding its parameters scientifically are a fairly effective way to realize the drawing technology demand. This paper established kinematics mode of the six-bar drawing mechanism by bar-group method...

Introduction Four-bar linkage knee mechanisms for the trans-femoral amputee are widely available, but although they may offer functional advantages to certain amputees, they are fitted in a limited number of cases. It may be assumed that one reason for this is that persons responsible for prescription and fitting may not be familiar with the kinematic characteristics and possible advantages of ...

The paper provides experimental evidence to support the recently introduced Switching Four-bar Mechanism (SFM) model as a template for small-scale legged locomotion in quasi-static operation regimes. The evidence suggests that the SFM is suitable for capturing salient motion behaviors—or motion primitives—for multiple, morphologically distinct miniature legged robots. Such primitives can be use...

PURPOSE We investigate the dependence of the kinematics of the human knee on its anatomy. The idea of describing the kinematics of the knee in the sagittal plane using four-bar linkage is almost as old as kinematics as an independent discipline. We start with a comparison of known four-bar linkage constructions. We then focus on the model by H. Nägerl which is applicable under form closure. M...

Modulation-transfer-function (MTF) measurement often involves the use of three- and four-bar resolution targets. In the conversion of three- and four-bar image data to MTF, biased results can occur when we use series-expansion techniques appropriate for square-wave targets of infinite extent. For systems where the image data are digitally recorded, a convenient and accurate conversion of bar-ta...