BACKGROUND/AIMS The transmembrane proteins Neph1 and nephrin form a complex in the slit diaphragm (SD) of podocytes. As recent studies indicate an involvement of this complex in the polymerization of the actin cytoskeleton and proteinuria, we wanted to study the subcellular localization of Neph1 in the normal human kidney and its expression in focal segmental glomerulosclerosis (FSGS), minimal ...

Autism spectrum disorders (ASDs) have long been noted to affect many more males than females, and accordingly, sex-specific factors have been hypothesized to increase males’ risk for, or protect females from, ASDs. However, no such factor has been definitively implicated in ASD etiology that can account for its male-biased prevalence, nor is it known whether the major drivers of sex-differentia...

This paper describes modeling and simulation for the growth and dissolution of oxygen precipitates in Czochralski silicon(CZ) wafers during heat treatment. Growth and dissolution rates arc newly derived and inserted into a set of chemical rate equations(CILEs) and a Fokkor-Planck equation(FPE). Annealing ambients and surface conditions are taken into account for solving continuity equations in ...

Supplementary Material A. Background on Fokker-Planck Equation The Fokker-Planck equation (FPE) associated with a given stochastic differential equation (SDE) describes the time evolution of the distribution on the random variables under the specified stochastic dynamics. For example, consider the SDE: dz = g(z)dt+N (0, 2D(z)dt), (16) where z ∈ R, g(z) ∈ R, D(z) ∈ Rn×n. The distribution of z go...

In this paper, we show that a small minimal blocking set with exponent e in PG(n, pt), p prime, spanning a (t/e − 1)-dimensional space, is an Fpe-linear set, provided that p > 5(t/e)− 11. As a corollary, we get that all small minimal blocking sets in PG(n, pt), p prime, p > 5t−11, spanning a (t−1)-dimensional space, are Fp-linear, hence confirming the linearity conjecture for blocking sets in t...

O ensino da Física de Partículas Elementares (FPE), com a escassez materiais didáticos Moderna e Contemporânea no médio, percebemos necessidade elaborar uma sequência didática o suporte das Tecnologias Informação Comunicação (TICs), na aprendizagem baseada em jogos digitais. física já era muito complicado para alguns estudantes, deficitária compreensão do tema presença dela constante cotidiano ...

With the development of cloud computing and big data, data privacy protection has become an urgent problem to solve. Data encryption is the most effective way to protect privacy; however, it will change the data format and result in: 1. database structure and application software will be changed; 2. structured query language (SQL) operations cannot work properly, especially in SQL-based fuzzy q...

Gamma oscillations of the local field potential are organized by collective dynamics of numerous neurons and have many functional roles in cognition and/or attention. To mathematically and physiologically analyse relationships between individual inhibitory neurons and macroscopic oscillations, we derive a modification of the theta model, which possesses voltage-dependent dynamics with appropria...