THE general association of high blood cholesterol levels with atherosclerosis has been almost universally accepted. Because of this association, doctors attempting to treat the disease have sought means to lower circulating cholesterol and thereby, possibly, to arrest or perhaps even to reverse the process of vascular deposition and narrowing. Numerous drugs employed to the present have achieve...

Metformin and berberine have been reported to have lipid lowering effects. This study aims to investigate lipid lowering effects of berberine and metformin, alone and in combination, in HepG2 cells to determine whether berberine and metformin work synergistically and elucidate their mechanisms. HepG2 cells were treated with 33 mM glucose in the presence of various concentrations of berberine an...

Metformin and berberine have been reported to have lipid lowering effects. This study aims to investigate lipid lowering effects of berberine and metformin, alone and in combination, in HepG2 cells to determine whether berberine and metformin work synergistically and elucidate their mechanisms. HepG2 cells were treated with 33 mM glucose in the presence of various concentrations of berberine an...

BACKGROUND Diabetes mellitus (DM) is common in patients hospitalized with an acute myocardial infarction (AMI), representing in some cases the first opportunity to recognize and treat DM. We report the incidence of new DM and its recognition among patients with AMI. METHODS AND RESULTS Patients in a 24-site US AMI registry (2005-08) had glycosylated hemoglobin assessed at a core laboratory, w...

The present study explores the effect of renewable energy consumption and public-private partnership investment in on consumption-based carbon dioxide emissions for India from 1990Q1 2015Q4 whilst controlling technology innovation economic growth. employs Maki cointegration, Bayer-Hanck fully modified ordinary least squares, dynamic frequency-domain causality tests to explore these dynamics. ou...

A radio frequency (rf) plasma source is operated at 2 MHz under an expanding magnetic field. The consists of a 14-cm-diameter and 25-cm-long tube wound by seven-turn rf loop antenna powered via impedance matching circuit. efficient power transfer to the demonstrated, high-density above 1012 cm−3 successfully obtained for kW level power. radial density profile having center peak observed both in...

The objective of the present investigation was to design a vesicular formulation of brimonidine tartrate and evaluate its ability to reduce the dosing frequency and improve the therapeutic efficacy of the drug. Nano-vesicles of brimonidine tartrate were prepared by film hydration method. The prepared vesicles were evaluated for photomicroscopic characteristics, entrapment efficiency, in vitro, ...

OBJECTIVE To determine the effect of lowering the fasting plasma glucose (FPG) criterion for impaired fasting glucose (IFG) on the prevalence of IFG, the risks of diabetes, and cardiovascular disease (CVD) associated with IFG. RESEARCH DESIGN AND METHODS Three studies were used: 1). the 1998 National Health Survey (NHS98), a randomly selected cross-sectional sample of 4723 subjects; 2). the S...

To study the possible interference of low frequency noise on performance and annoyance, subjects categorised as having a high- or low sensitivity to noise in general and low frequency noise in particular worked with different performance tasks in a noise environment with predominantly low frequency content or flat frequency content (reference noise), both at a level of 40 dBA. The effects were ...

likelv that L donovani was of animal origin, as were other members of the genus, and in Brazil, foxes are a significant animal reservoir. The sensitivity of the Brazilian disease to antimonial drugs does not fit with the resistance of the infantum subspecies found in Portugal. Today there are epidemics of kala-azar among poor children in favelas in cities of north eastern Brazil such as Teresin...