The present study reported the synthesis and antihyperglycemic activity of 1,4-benzothiazepines (1,4-benzothiazepine-2-one derivatives) in alloxan-induced diabetic rats. (3a-i) were synthesized via Friedel-Crafts acylation, reduction microwave assisted S-alkylation reactions characterized by Fourier transform infrared spectroscopy, proton nuclear magnetic resonance, mass elemental analysis. In ...
