BACKGROUND Levels of tumor necrosis factor-alpha (TNF-alpha) increase with acute ischemia. However, whether elevations of TNF-alpha in the stable phase after myocardial ischemia (MI) are associated with increased risk of recurrent coronary events is unknown. METHODS AND RESULTS A nested case-control design was used to compare TNF-alpha levels obtained an average of 8.9 months after initial MI...

Activation of the basal ganglia has been shown during the preparation and execution of movement. However, the extent to which the activation during movement is related to efferent processes or feedback-related motor control remains unclear. We used motor imagery (MI), which eliminates peripheral feedback, to further investigate the role of the subthalamic area in the feedforward organization of...

BACKGROUND Patients with myocardial infarction (MI) and concomitant chronic obstructive pulmonary disease (COPD) constitute a high-risk group with increased mortality. β-Blocker therapy has been shown to reduce mortality, prevent arrhythmias, and delay heart failure development after an MI in broad populations. However, the effect of β-blockers in COPD patients is less well established and they...

OBJECTIVE We carried out a secondary analysis in high-risk patients with a previous myocardial infarction (MI) and diabetes in the Alpha Omega Trial. We tested the hypothesis that in these patients an increased intake of the n-3 fatty acids eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and α-linolenic acid (ALA) will reduce the incidence of ventricular arrhythmias and fatal MI. RES...

BACKGROUND Recurrence after laparoscopic ventral hernioplasty is a severe problem despite surgeons' increased experience in recent years. It is well known that the main reasons for recurrences are lack of experience, bad technique, infection, and seroma. The aim of this study was to investigate the events, what caused recurrences, and the technique to prevent recurrence in laparoscopic ventral ...

Anti-Mi-2 autoantibody is strongly associated with dermatomyositis and found in sera of 20% of patients. Mi-2 antigen contains at least eight components and previous evidence suggested that the 240-kD protein was the antigenic component for at least some sera. In this study, anti-M-2 patient sera were used to screen human thymocyte and HeLa cell lambda gt11 expression libraries, and two clones ...

Neural activity in primary motor cortex (MI) is known to correlate with hand position and velocity. Previous descriptions of this tuning have (1) been linear in position or velocity, (2) depended only instantaneously on these signals, and/or (3) not incorporated the effects of interneuronal dependencies on firing rate. We show here that many MI cells encode a superlinear function of the full ti...

this study was conducted to determine whether precordial st segment depression in admission electrocardiogram (ecg) in patients with acute phase inferior myocardial infarction (mi) eligible for thrombolytic therapy and subsequent angiographic evaluation, influences the incidence of left anterior descending artery (lad) disease. 31 consecutively admitted patients were entered in our study. 20 pa...

The purpose of this study is to investigate the impact oxygen therapy on cardiovascular outcomes in relation sex patients with confirmed myocardial infarction (MI). DETermination role Oxygen suspected Acute Myocardial Infarction trial randomized 6,629 at 6 L/min for 6-12 hours or ambient air. In present subgroup analysis including 5,010 (1,388 women and 3,622 men) MI, we report effect supplemen...