Among the hyphomycetous endoparasites destructive to eelworms that abound in slowly decaying plant materials, as well as in agar plate cultures earlier inoculated with partly decomposed vegetable detritus, Harposporium anguillulae Lohde emend. Zopf (1888) is observed much more frequently than allied forms. In seeking an explanation for this more frequent occurrence it would seem highly signific...

This paper describes a physiologically based toxicokinetic model for 1,3-butadiene uptake, distribution, and metabolic clearance in mice. Model parameters for metabolic activity were estimated from the correspondence between computer simulation studies and experimental results as published in the literature. The parameterized model was validated with independent literature data. With the result...

Using Taylor's series we propose a modified secant relation to get a more accurate approximation of the second curvature of the objective function. Then, based on this modified secant relation we present a new BFGS method for solving unconstrained optimization problems. The proposed method make use of both gradient and function values while the usual secant relation uses only gradient values. U...