in this study, we synthesized herceptin conjugated magnetic nanoparticles (hmns) as an alternative probe to discover the levels of her2 (human epidermal growth factor receptor-2) in the surface of cells. these nanoparticles can be used by magnetic resonance imaging (mri) (non-invasive methods) for screening the patients with her2 positive or negative tumors. dextran coated iron oxide nanopartic...

results the maximum si was obtained at the highest applied flip angle (45°). the linear relationship between si and nanoparticle concentration was seen up to 112.21 and 98.83 μmol fe/l for the short (10°) and the long (45°) flip angles, respectively (r2 = 0.95). these values were reduced up to 48.54 and 42.73 μmol fe/l for these flip angles with r2 of 0.99. conclusions the maximum si will be in...

background: increased impervious surfaces in urban areas not only increase runoff volume and peak flow, but also worsen urban storm water pollution. the polluted runoff has many adverse impacts on human life and environment. the purpose of this study was to investigate and compare the efficiency of sand columns coated with nanoparticles of iron oxide in the presence and absence of a magnetic fi...

An antibody-directed nonviral vector, polyethylene glycol-grafted polyethylenimine functionalized with superparamagnetic iron oxide nanoparticles and a gastric cancer-associated CD44v6 single-chain variable fragment (scFv(CD44v6),-PEG-g-PEI-SPION), was constructed as a gastric cancer-targeting and magnetic resonance imaging (MRI)-visible nanocarrier for small interfering RNA (siRNA) delivery. B...

PURPOSE To evaluate spin-lock MR for detecting superparamagnetic iron oxides and compare the detection sensitivity of quantitative T1ρ with T2 imaging. METHODS In vitro experiments were performed to investigate the influence of iron oxide particle size and composition on T1ρ . These comprise T1ρ and T2 measurements (B0 = 1.41T) of agar (2%) with concentration ranges of three different iron ox...

Stable superparamagnetic iron oxide nanoparticles (SPIONs), which can be easily dispersed in an aqueous medium and exhibit high magnetic relaxivities, are ideal candidates for biomedical applications including contrast agents for magnetic resonance imaging. We describe a versatile methodology to render water dispersibility to SPIONs using tetraethylene glycol (TEG)-based phosphonate ligands, wh...

in recent years, the scientists have focused on nanotecnology and its applications as the most important fields of research and development. the use of nanoparticles offers many advantages, due to their unique size and physical properties. magnetic iron oxide nanoparticles have been used in many fields, because of their unique properties such as large specific surface area and convenient separa...

Iron oxide nanoparticles are used for contrast enhancement in magnetic resonance imaging (MRI). We have prepared gold-coated iron oxide nanoparticles that show no change in their superparamagnetic behavior as a consequence of coating. Their potential use as MRI contrast agents was investigated by monitoring their T2 relaxation time with concentration. Cytotoxicity of these nanoparticles was als...

Enhanced S(1)--> T(1) intersystem crossing of silicon phthalocyanine (SiPc) owing to iron oxide nanoparticles and intense MCD signal of diamagnetic SiPc have been experimentally shown by using SiPcs supported on magnetic silica gel, in which the iron oxide nanoparticles were effectively dispersed.

Dietary iron oxide nanoparticles are shown to ameliorate neurodegeneration in a Drosophelia Alzheimer's disease model. Iron oxide nanoparticles can mimic catalase and can decompose reactive oxygen species (ROS). This has potential therapeutic uses for aging, metabolic disorders, and neurodegenerative diseases, in which increased production of ROS is closely implicated.