Recent research has shown that low genetic variation in individuals can increase susceptibility to infection and group living may exacerbate pathogen transmission. In the eusocial diploid termites, cycles of outbreeding and inbreeding characterizing basal species can reduce genetic variation within nestmates during the life of a colony, but the relationship of genetic heterogeneity to disease r...

Fungi inhabit every natural and anthropogenic environment on Earth. They have highly varied life-styles including saprobes (using only dead biomass as a nutrient source), pathogens (feeding on living biomass), and symbionts (co-existing with other organisms). These distinctions are not absolute as many species employ several life styles (e.g. saprobe and opportunistic pathogen, saprobe and myco...

Fungal secretory peroxidases mediate fundamental ecological functions in the conversion and degradation of plant biomass. Many of these enzymes have strong oxidizing activities towards aromatic compounds and are involved in the degradation of plant cell wall (lignin) and humus. They comprise three major groups: class II peroxidases (including lignin peroxidase, manganese peroxidase, versatile p...

BACKGROUND Genome-wide association studies have identified the ORM (yeast)-like protein isoform 3 (ORMDL3) gene locus on human chromosome 17q to be a highly significant risk factor for childhood-onset asthma. OBJECTIVE We sought to investigate in vivo the functional role of ORMDL3 in disease inception. METHODS An Ormdl3-deficient mouse was generated and the role of ORMDL3 in the generation ...

allergic fungal sinusitis (afs) has been clinicopathologically defined as a noninvasive form of fungal infection. this study was designed to distinguish afs among patients with chronic sinusitis who failed to respond to repeated courses of antibiotics and were therefore candidates for functional endoscopic sinus surgery (fess) in sari. allergic mucin and sinus lavage was collected during fess f...

A STUDY DONE at our institution between 1981 and 1983 showed that 42% of liver recipients developed invasive fungal infections, mostly due to Candida and Aspergillus. l Between July 1984 and September 1985 we studied 101 consecutive adult liver transplant recipients at Presbyterian University Hospital for the incidence and risk factors associated with invasive fungal infection. The risk factors...

Abstract Ramularia leaf spot disease (RLS) is one of the most dominating fungal diseases in barley. The typically appears late season after flowering and results a rapid loss photosynthetic area. A recent decline fungicide efficacy lack RLS-resistant cultivars hamper effective control. Global warming will provoke increasing droughts which influence host plant physiology probably affect outbreak...

Background: Fungal aeroallergens might sensitize the airway which in turn produces a specific cytokine profile. Objective: To evaluate the IL-25 and IL-33 profile in patients with fungal allergic rhinitis. Methods: The present study examined patients who were evaluated due to allergic rhinitis (AR) at Emam Reza Hospital of Shiraz, Iran. The all...