Objective(s) Achillea genius is widely used in traditional medicine for gastrointestinal disorders. The aim of this study was to investigate the effects of aqueous-ethanol extract of Achillea wilhelmsii on rat’s gastric motility in basal and vagal stimulated conditions. Materials and Methods Twenty four Wistar rats were randomly divided into two groups: control and test. The extract was prep...

EDITORIAL SYNOPSIS Basal and maximal (post-histamine) acid outputs were significantly reduced in patients with cirrhosis. A subnormal secretory response to stimulation with peptone was also found. Gastric hyposecretion was not related to the aetiology or severity of the hepatic disease nor to the extent or presence of a portal-collateral circulation. Increased gastric production of ammonia in c...

BACKGROUND Cryptosporidiosis has been shown to be a common cause of diarrhoea in both immunocompetent and immunosuppressed individuals. There are very few data on the distribution of Cryptosporidium parvum along the gastrointestinal tract. AIMS To evaluate the location of Cryptosporidium parasites in the digestive tract of patients with AIDS. METHODS Gastrointestinal localisation of C parvu...

CagA, encoded by cytotoxin-associated gene A (cagA), is a major virulence factor of Helicobacter pylori, a gastric pathogen involved in the development of upper gastrointestinal diseases. Infection with cagA-positive H. pylori may also be associated with diseases outside the stomach, although the mechanisms through which H. pylori infection promotes extragastric diseases remain unknown. Here, w...

BACKGROUND Pyloric cells with "glassy" cytoplasm were detected 20 years ago in the human gastric mucosa, and subsequently in the gastric mucosa of two baboons and of transgenic mice. These pyloric cells, called glassy cells (GCs) show a homogeneous, eosinophilic material that pushes the nucleous towards the free border of the cell. MATERIALS AND METHODS The frequency of baboons having pyloric...

Dyspepsia refers to a condition of impaired digestion which has a yearly incidence of approximately 1%, and the prevalence of around 20-30%. Although the etiology of dyspepsia varies, an organic cause is found in only 40% of the patients. In the differential diagnosis of dyspepsia, cardiac, hepatobiliary, pancreatic, and intestinal disorders and gastroesophageal reflux disease can be eliminated...

The article explores modern concepts about functional gastrointestinal disorders in children, considers features of the classification according to Rome criteria and Russian clinical guidelines, presents evolution views context understanding general pathophysiological mechanism as impaired “gut-brain” interactions, which leads dysmotility different parts tract, visceral hypersensitivity, change...

BACKGROUND Although subacute and chronic gastrointestinal symptoms are very common in primary care, epidemiological date are sparse. The aim of the study was to examine and quantify the prevalence of subacute and chronic gastrointestinal symptoms and their associations with somatic and mental disorders in the general population. METHODS Data were collected prospectively between 1981 (age m = ...

The sensitivity for one's own internal body signals (i.e., interoception) has been demonstrated to play an important role in the pathogenesis of eating and weight disorders. Most previous measures assessing interoceptive processing have not, or only partly, captured perception of hunger and satiety cues, which is a core aspect of interoceptive deficits in eating disorders. In addition, methods ...

Trichobezoar is a rare condition caused by the accumulation of foreign material, specifically hair, into gastrointestinal tract. Underlying psychiatric disorders are common among patients diagnosed with bezoars. This most commonly associated trichophagia, trichotillomania might also be present. Typically, this disorder acquainted in adolescent females who complain alopecia, along an upper abdom...